DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and NNK1

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_012750.1	Gene:	NNK1 / 853683	SGDID:	S000001654	Length:	928	Species:	Saccharomyces cerevisiae

Alignment Length:	320	Identity:	66/320 - (20%)
Similarity:	124/320 - (38%)	Gaps:	83/320 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LVISRAHFKDFPALLQGVTESLKRHVLLRSAIAHFRRTDGSHLTSLSCFRETDIVICCCKNEEII 103
            ::|..|...|:.|::     ||.:..:|.|:.::|         ||:.|.....|.....|::.|
Yeast   329 VIIEHAPSHDYKAMM-----SLVKKFMLTSSRSNF---------SLAGFANNASVSQATANDDNI 379

  Fly   104 CVKYSINKDFQRMVDSCKRWGQHHLDSGTLES---------------MKSHDL---------PEA 144
            ..:.:.|......|::.......|   |::.|               |.|:.|         |:.
Yeast   380 NSRNTPNNSNDTYVNTRPLQRSRH---GSIASQFLSSFSPSMTSIAKMNSNPLSGSAGGSARPDD 441

  Fly   145 IQLYIETIEPVEHNTRTLIYRG-----------QTRANRTKCTVKMVNKQTQSNDRGDTYMEAEV 198
                 :.:|.:.|....:|..|           :|...|   .:|:|..:...|.:.....|..:
Yeast   442 -----KGMEILGHRLGKIIGFGAWGIIRECFDIETGVGR---VIKIVKFKGHQNIKKHVLREVAI 498

  Fly   199 LRQLQSHPNIIELM-YTVEDERYMYTVLEHL-DCNMQKVI-----QKRGILSEADARSVMRC--- 253
            .|.|: |..|:.|: :.::|...||.:.|.: |..:..::     .||..:..|:     ||
Yeast   499 WRTLK-HNRILPLLDWKLDDNYAMYCLTERINDGTLYDLVISWDEFKRSKIPFAE-----RCRLT 557

  Fly   254 ------TVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGSKLY 307
                  .:|||.:||...::|.|||.||.|:.....|.::| |.:.:|.::.::....:|
Yeast   558 IFLSLQLLSALKYMHSKTIVHGDIKLENCLLQKEGKKSDWK-VFLCDFGMSCHFDEKHVY 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711	15/68 (22%)
		S_TKc	164..409	CDD:214567	39/171 (23%)
		PKc_like	164..403	CDD:304357	39/171 (23%)
NNK1	NP_012750.1	PKc	455..>613	CDD:270622	39/167 (23%)
NNK1	NP_012750.1	PKc_like	<817..864	CDD:419665
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900