DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and IKS1

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_012478.3	Gene:	IKS1 / 853389	SGDID:	S000003593	Length:	667	Species:	Saccharomyces cerevisiae

Alignment Length:	141	Identity:	32/141 - (22%)
Similarity:	58/141 - (41%)	Gaps:	33/141 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 LSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWN---------------FKMVK 291
            ||.....|::|.....|..:|.:.:||||:||.|.|:.:.....|               |..:.
Yeast   322 LSTEQLVSIIRDIARGLHELHSIGLIHRDLKPSNCLLLTPFKSDNENDNVYDREHNSDEFFPSIV 386

  Fly   292 VANFDLATYYRGSKLYVRC-GTPCYMAPEMI-----------------AMSGYDYQVDSWSLGVT 338
            :.:...:.....|:|...| ||..:.||::|                 ..:.|.:..|.:|||:.
Yeast   387 IGDLGESQLEGESRLGTGCTGTLEFTAPDLIIQGRPVSSSTLPSRSSHTYNEYTFASDMYSLGMI 451

  Fly   339 LFYMLCGKMPF 349
            .::::.|::||
Yeast   452 CYFIVFGELPF 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	32/141 (23%)
		PKc_like	164..403	CDD:304357	32/141 (23%)
IKS1	NP_012478.3	PKc_like	173..522	CDD:419665	32/141 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900