DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and KIN2

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_013197.1	Gene:	KIN2 / 850785	SGDID:	S000004086	Length:	1147	Species:	Saccharomyces cerevisiae

Alignment Length:	328	Identity:	86/328 - (26%)
Similarity:	148/328 - (45%)	Gaps:	56/328 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 VKYSINKDFQRMVDSCKRWGQHHLDSGTLESMKSHDLPEAIQLYIETIEPVEHNTRTLIYRGQTR 169
            :|....:..||..|:.:       .:|.:|..:.|........::||:.........|:...||
Yeast    65 IKQGKEQAAQRQNDASR-------PNGAVELRQFHRRSLGDWEFLETVGAGSMGKVKLVKHRQT- 121

  Fly   170 ANRTKCTVKMVNKQTQS------------ND----RGDTYMEAEVLR-----------QLQSHPN 207
              :..|.:|:||:.:::            |:    .....:|.|:.|           |:..||:
Yeast   122 --KEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPH 184

  Fly   208 IIELMYTVEDERYMYTVLEHLDCN--MQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIHRD 270
            |..|........:.|.:.|::...  :..:|| .|.|.|..||...|...|||.::|...::|||
Yeast   185 ICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQ-HGSLKEHHARKFARGIASALQYLHANNIVHRD 248

  Fly   271 IKPENLLVCSSSGKWNFKMVKVANFDLATY--YRGSKLYVRCGTPCYMAPEMIAMSGY-DYQVDS 332
            :|.||::: ||||:     :|:.:|.|:..  || .:|:..||:..:.|||::....| ..:||.
Yeast   249 LKIENIMI-SSSGE-----IKIIDFGLSNIFDYR-KQLHTFCGSLYFAAPELLKAQPYTGPEVDI 306

  Fly   333 WSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYR 397
            ||.|:.|:.::|||:||..  :||..::..|..|...||    |.:|.|...|:..::|.||..|
Yeast   307 WSFGIVLYVLVCGKVPFDD--ENSSILHEKIKKGKVDYP----SHLSIEVISLLTRMIVVDPLRR 365

  Fly   398 VPI 400
            ..:
Yeast   366 ATL 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711	1/2 (50%)
		S_TKc	164..409	CDD:214567	76/269 (28%)
		PKc_like	164..403	CDD:304357	76/269 (28%)
KIN2	NP_013197.1	STKc_Kin1_2	97..377	CDD:270979	79/289 (27%)
KIN2	NP_013197.1	KA1	1104..1147	CDD:396635
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345251
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930