DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and CMK1

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_116669.1	Gene:	CMK1 / 850568	SGDID:	S000001910	Length:	446	Species:	Saccharomyces cerevisiae

Alignment Length:	282	Identity:	80/282 - (28%)
Similarity:	132/282 - (46%)	Gaps:	44/282 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 IEPVEHNTRTLIYRGQT----------RANRTK----CTVKMVNKQTQSNDRGD---TYMEAEVL 199
            ::|..:..:.....|:|          :|..|:    ..||::.|:....::..   .|.|.::|
Yeast    26 VQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDIL 90

  Fly   200 RQLQSHPNIIEL--MYTVEDERYMYTVL----EHLDCNMQKVIQKRGILSEADARSVMRCTVSAL 258
            ::|. ||||:..  .:..:|:.|:.|.|    |..|     .|.|:|..:|.||..::...:||:
Yeast    91 QRLH-HPNIVAFKDWFESKDKFYIITQLAKGGELFD-----RILKKGKFTEEDAVRILVEILSAV 149

  Fly   259 AHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGSK--LYVRCGTPCYMAPEMI 321
            .:||...::|||:||||||....|.:   ..:.||:|.:|...:..:  ||...|:..|:|||::
Yeast   150 KYMHSQNIVHRDLKPENLLYIDKSDE---SPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVL 211

  Fly   322 AMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDM-----ESVMSPE 381
            ...|:....|.||:||..:.:|||...|.:  :..::......:|  .||...     :|| |.:
Yeast   212 TQDGHGKPCDIWSIGVITYTLLCGYSAFRA--ERVQDFLDECTTG--EYPVKFHRPYWDSV-SNK 271

  Fly   382 ATQLIDGLLVSDPSYRVPIAEL 403
            |.|.|...|..|||.|...|||
Yeast   272 AKQFILKALNLDPSKRPTAAEL 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	79/270 (29%)
		PKc_like	164..403	CDD:304357	77/268 (29%)
CMK1	NP_116669.1	STKc_CAMK	36..298	CDD:270687	79/272 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900