DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and camk1b

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_021335371.1	Gene:	camk1b / 794026	ZFINID:	ZDB-GENE-141014-1	Length:	394	Species:	Danio rerio

Alignment Length:	264	Identity:	71/264 - (26%)
Similarity:	126/264 - (47%)	Gaps:	24/264 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 HDLPEAI--QLYIETIEPVEHNTRTLIYRGQTRANRTKCTVKMVNKQTQSNDRGDTYMEAEVLRQ 201
            :|..|.:  ..:.|.:...|..||.|:            .||.:.|:...........|..||.:
Zfish    33 YDFKEVLGTGAFSEVMLAEEKRTRKLV------------AVKCIAKKALEGKENSIENEIAVLHK 85

  Fly   202 LQSHPNIIELMYTVEDERYMYTVLEHLDCN--MQKVIQKRGILSEADARSVMRCTVSALAHMHQL 264
            :: |.||:.|....|.:.::|.|::.:...  ..::::| |..:|.||..:::..:.|:.::|.:
Zfish    86 IK-HANIVSLEDIFESKSHLYLVMQLVSGGELFDRIVEK-GFYTEKDASKLIQQILDAVKYLHDM 148

  Fly   265 QVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYY-RGSKLYVRCGTPCYMAPEMIAMSGYDY 328
            .::|||:||||||..|...:   ..:.:::|.|:... .||.:...||||.|:|||::|...|..
Zfish   149 GIVHRDLKPENLLYYSMDEE---SKIMISDFGLSKIEGSGSVMSTACGTPGYVAPEVLAQKPYSK 210

  Fly   329 QVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSD 393
            .||.||:||..:.:|||..||..  :|..:::..|:.....:.......:|..|...|..|:..|
Zfish   211 AVDCWSIGVIAYILLCGYPPFYD--ENDAKLFEQILRAEYEFDSPYWDDISDSAKDFIVHLMEKD 273

  Fly   394 PSYR 397
            |:.|
Zfish   274 PNQR 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	64/237 (27%)
		PKc_like	164..403	CDD:304357	64/237 (27%)
camk1b	XP_021335371.1	PKc_like	29..291	CDD:328722	71/264 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900