DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and uhmk1

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001070127.1	Gene:	uhmk1 / 767721	ZFINID:	ZDB-GENE-060929-1014	Length:	410	Species:	Danio rerio

Alignment Length:	306	Identity:	81/306 - (26%)
Similarity:	125/306 - (40%)	Gaps:	65/306 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 SGTLESMKSHDLPEAIQLY--IETIEP-VEHNTRTLIYRGQTRANRTKCTVKMVNKQTQSNDRGD 191
            |.|.|...|   |...::|  |..::. :.......:||  ..:.|....||......|..|.|
Zfish     5 SATAEQKAS---PALFEIYGKIWNVQARLGQGVSASVYR--VSSGRATSAVKEFQVDPQGGDYG- 63

  Fly   192 TYM-EAEVLRQLQSHPNIIEL--MYTVEDERYMYT---VLEHLDCNMQKVIQKRG------ILSE 244
             |: |:.||.::|.|.||:.|  |:|..:...:.|   :||.||.::.:::.:..      .|.:
Zfish    64 -YLKESSVLEKIQGHKNIVTLYGMFTNHNPFGVATHCLLLELLDVSVSELLVRASNQGHSMWLIQ 127

  Fly   245 ADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWN-----FKMVKVANFDLATYYRGS 304
            ..||.|:    .||..:|:...:|.|:||.|:|       |:     ||::   :|.| ::..|.
Zfish   128 HCARDVL----EALTFLHREGFVHADLKPRNVL-------WSADDECFKLI---DFGL-SFKEGH 177

  Fly   305 KLYVRCGTPCYMAPE-----MIAMSGYDYQ------VDSWSLGVTLFYMLCGKMPFASACK---- 354
            :......|..|.|||     .:|.:|.:..      ||.||||:.|..|..| |......|
Zfish   178 QDVKYIQTDGYRAPEAELQNSLAQAGVESDSGCTTAVDLWSLGIVLLEMYSG-MKLKETVKSQEW 241

  Fly   355 --NSKEIYAAIMSGGP-TYPKDMESVMSPEATQLIDGLLVSDPSYR 397
              ||..|...|.|... .||    ::.......||..:|.:||..|
Zfish   242 KDNSSAIVDHIFSSNALVYP----AIPVFHLRDLIKSMLHNDPKLR 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	74/269 (28%)
		PKc_like	164..403	CDD:304357	74/269 (28%)
uhmk1	NP_001070127.1	STKc_KIS	23..299	CDD:270922	75/285 (26%)
		S_TKc	24..295	CDD:214567	74/284 (26%)
		RRM_UHMK1	309..396	CDD:240911
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900