Protein Alignment CG10177 and Dclk2

DIOPT Version :9

• Sequence 1: NP_651150.1
• Gene: CG10177 / 42772
• FlyBaseID: FBgn0039083
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001344389.1
• Gene: Dclk2 / 70762
• MGIID: 1918012
• Length: 772
• Species: Mus musculus
• Alignment Length: 654
• Identity: 144/654 - (22%)
• Similarity: 217/654 - (33%)
• Gaps: 277/654 - (42%)

  Fly     5 STSLGSRRVGP--------PLH------------------KKALRVCFLRNGDRHFKGVNLVISR 43
            |:|.||...||        |.|                  |||.:..|.|||||:|||:...||.
Mouse    29 SSSGGSSISGPKGNGLIPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVFAISN 93

  Fly    44 AHFKDFPALLQGVTESLKRHVLLRSAIAHFRRTDGSH-LTSLSCFRETDIVICCCKNEEIICVKY 107
            ..|:.|.|||..:|.||..:|.|...:......|||. :|||....|.:..: |..||....|.|
Mouse    94 DRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYV-CASNEPFRKVDY 157

  Fly   108 SIN-----------------------------KDF--QRMVDSCKRWGQHHLDSGT--------- 132
            :.|                             |||  .::|...:        ||.
Mouse   158 TKNVNPNWSVNIKGGTTRTLAVASAKSEVKESKDFIKPKLVTVIR--------SGVKPRKAVRIL 214

  Fly   133 LESMKSH-------DLPEAIQL--------------------------------------YIETI 152
            |....:|       |:.|||:|                                      |.:..
Mouse   215 LNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKYRYAQDD 279

  Fly   153 EPVEHNTRTLIYRGQTRANRTKCT----------------------------------------- 176
            ..::|:...::....:||:..|.:
Mouse   280 FVLDHSECRVLKSSYSRASAAKYSGSRSPGFSRRSKSPASVKRAGHSSAYSTAKSPVNGTPSSQL 344

  Fly   177 ---------------------VKMVNKQ--TQSNDRG---------------------------- 190
                                 :|.::.|  :.||..|
Mouse   345 STPKSTKSSSSSPTSPGSFRGLKQISAQGRSSSNVNGGPELDRCLSPEGVNGNRCSESFPLLEKY 409

  Fly   191 ------------------DTYM-----------------------EAEVLRQLQSHPNIIELMYT 214
                              |.|.                       |..:||::: |||||.|:..
Mouse   410 RIGKVIGDGNFAVVKECVDRYTGKEFALKIIDKAKCCGKEHLIENEVSILRRVK-HPNIIMLVEE 473

  Fly   215 VEDERYMYTVLEHLDCNMQKVIQKRGIL----------SEADARSVMRCTVSALAHMHQLQVIHR 269
            :|....::.|:|         :.|.|.|          :|.|..:::....:||.::|.|.::||
Mouse   474 METATDLFLVME---------LVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSIVHR 529

  Fly   270 DIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGSKLYVRCGTPCYMAPEMIAMSGYDYQVDSWS 334
            ||||||||||....  ..|.:|:.:|.|||...| .||..||||.|:|||:||.:||..:||.|:
Mouse   530 DIKPENLLVCEYPD--GTKSLKLGDFGLATVVEG-PLYTVCGTPTYVAPEIIAETGYGLKVDVWA 591

  Fly   335 LGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVP 399
            .||..:.:|||..||.|.....::::..|::|...:|......::..|.:||..:|..:...|..
Mouse   592 AGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCT 656

  Fly   400 IAEL 403
            ..|:
Mouse   657 AGEI 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711	36/108 (33%)
		S_TKc	164..409	CDD:214567	84/383 (22%)
		PKc_like	164..403	CDD:304357	83/381 (22%)
Dclk2	NP_001344389.1	DCX	67..157	CDD:214711	35/90 (39%)
		DCX	191..279	CDD:214711	13/95 (14%)
		PKc_like	407..665	CDD:328722	76/267 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770