DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and Dapk3

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_006241053.1	Gene:	Dapk3 / 64391	RGDID:	621766	Length:	464	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	67/269 - (24%)
Similarity:	128/269 - (47%)	Gaps:	16/269 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 EAIQLYIETIEPVEHNTRTLIYRGQTRANRTKCTVKMVNK-QTQSNDRG----DTYMEAEVLRQL 202
            |.::.:.|..|.:......::.:.|.:....:...|.:.| :..|:.||    :...|..:||::
  Rat    23 EDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREI 87

  Fly   203 QSHPNIIELMYTVEDERYMYTVLEHLD-CNMQKVIQKRGILSEADARSVMRCTVSALAHMHQLQV 266
            : |||||.|....|::..:..:||.:. ..:...:.::..|:|.:|...::..:..:.::|..::
  Rat    88 R-HPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRI 151

  Fly   267 IHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYR---GSKLYVRCGTPCYMAPEMIAMSGYDY 328
            .|.|:||||:::......  ...:|:.:|.:|  :|   ||:.....|||.::|||::.......
  Rat   152 AHFDLKPENIMLLDKHAA--SPRIKLIDFGIA--HRIEAGSEFKNIFGTPEFVAPEIVNYEPLGL 212

  Fly   329 QVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSD 393
            :.|.||:||..:.:|.|..||....|  :|....|.:....:.::..|..|..|...|..|||.|
  Rat   213 EADMWSIGVITYILLSGASPFLGETK--QETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKD 275

  Fly   394 PSYRVPIAE 402
            |..|:.||:
  Rat   276 PKRRMTIAQ 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	64/248 (26%)
		PKc_like	164..403	CDD:304357	64/248 (26%)
Dapk3	XP_006241053.1	STKc_DAPK	23..291	CDD:271007	67/269 (25%)
Dapk3	XP_006241053.1	S_TKc	29..291	CDD:214567	66/263 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900