Protein Alignment CG10177 and dclk2a

DIOPT Version :10

• Sequence 1: NP_651150.1
• Gene: CG10177 / 42772
• FlyBaseID: FBgn0039083
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_073804849.1
• Gene: dclk2a / 572548
• ZFINID: ZDB-GENE-050420-170
• Length: 826
• Species: Danio rerio
• Alignment Length: 667
• Identity: 146/667 - (21%)
• Similarity: 217/667 - (32%)
• Gaps: 302/667 - (45%)

  Fly     5 STSLGSRRVGPPLH------------------KKALRVCFLRNGDRHFKGVNLVISRAHFKDFPA 51
            |.|.|:..|..|.|                  |||.:|.|.||||::|||:...:|...|:.|.|
Zfish    29 SGSRGNGIVPSPAHSAHCSFYRTRTLQSLTSEKKAKKVRFYRNGDKYFKGLVYAVSGDRFRSFDA 93

  Fly    52 LLQGVTESLKRHVLLRSAIAHFRRTD-GSHLTSLS---------C-----FRETDIV-------- 93
            ||..:|.||..:|.|...:......| |..:|||.         |     ||:.|..
Zfish    94 LLMELTRSLSDNVNLPQGVRSIYTADGGKKITSLDDLVEGESYVCASNEPFRKVDYTKNVNPNWS 158

  Fly    94 -------------ICCCKNE--------------------------------------------- 100
                         :...|||
Zfish   159 VNVKTGASRSMPSLTATKNELRERESKDYIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLT 223

  Fly   101 ----------------------EIIC--------------------------------------- 104
                                  :|||
Zfish   224 DITDAIKLDSGAVKRLYTLEGKQIICLQDFFGDDDVFIACGPEKYRYAQDDFVLDHSGKASTAFI 288

  Fly   105 -----------------VKYS-----------------------------------IN------- 110
                             |:||                                   ||
Zfish   289 TECQVIKSSYSARSAPPVRYSGSKSPGTGRRSKSPGSARRTAGHFSTNSQSPVKSPINGAPNSQI 353

  Fly   111 ----------------KDFQRMVDSC-KRWG----------QHHLDSGTLESMKSHDLPEAIQLY 148
                            :..:....|| ||.|          .||..:|.:..  |.:.|   |.:
Zfish   354 TTPKSAKSSSSSPTSPRSMRNFKFSCNKRMGVPVRLSVQIPTHHSSAGNVNG--SSETP---QHH 413

  Fly   149 IETIEPVEHNTRTLI-------YR-GQT--------------RANRTKCTVKMVNKQTQSNDRGD 191
            ..::.|..:..|.|.       |: |:.              |:...:..:|:::|   :..||.
Zfish   414 NNSLSPEVNGNRNLAASTILDKYKIGKVIGDGNFAVVKECVERSTGKEFALKIIDK---NKCRGK 475

  Fly   192 TYM---EAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHLDCNMQKVIQKRGIL----------S 243
            .::   |..|||::: |||||.|:..|:....:|.|:|         :.|.|.|          :
Zfish   476 EHLIENEVAVLRRVK-HPNIIMLIEEVDTPAELYLVME---------LVKGGDLFDAITSSTKYT 530

  Fly   244 EADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGSKLYV 308
            |.||..::....:||.::|::.::||||||||||||....  ..|.:|:.:|.|||...| .||.
Zfish   531 EKDASVMVFDLAAALKYLHRMCIVHRDIKPENLLVCEYPN--GTKSLKLGDFGLATVVEG-PLYT 592

  Fly   309 RCGTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKD 373
            .||||.|:|||:||.|||..:||.|:.||..:.:|||..||.|.....::::..|:.|...:|..
Zfish   593 VCGTPTYVAPEIIAESGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILLGHLEFPSP 657

  Fly   374 MESVMSPEATQLIDGLL 390
            ....:|..|.:||..:|
Zfish   658 FWDNISDSAKELIGHML 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711	40/266 (15%)
		S_TKc	164..409	CDD:214567	83/255 (33%)
dclk2a	XP_073804849.1	None