DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10177 and CAMK1G

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_065172.1	Gene:	CAMK1G / 57172	HGNCID:	14585	Length:	476	Species:	Homo sapiens

Alignment Length:	217	Identity:	70/217 - (32%)
Similarity:	113/217 - (52%)	Gaps:	23/217 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 DTYMEAE--VLRQLQSHPNIIELMYTVEDERYMYTVLEHLDCNMQKV--------IQKRGILSEA 245
            |:.:|.|  ||:::: |.||:    |:||   :|....|....||.|        |.:||:.:|.
Human    62 DSSLENEIAVLKKIK-HENIV----TLED---IYESTTHYYLVMQLVSGGELFDRILERGVYTEK 118

  Fly   246 DARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGSKLYVRC 310
            ||..|::..:||:.::|:..::|||:||||||..:.  :.|.| :.:.:|.|:...:...:...|
Human   119 DASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTP--EENSK-IMITDFGLSKMEQNGIMSTAC 180

  Fly   311 GTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDME 375
            |||.|:|||::|...|...||.||:||..:.:|||..||..  :...:::..|..|...:.....
Human   181 GTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYE--ETESKLFEKIKEGYYEFESPFW 243

  Fly   376 SVMSPEATQLIDGLLVSDPSYR 397
            ..:|..|...|..||..||:.|
Human   244 DDISESAKDFICHLLEKDPNER 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	70/217 (32%)
		PKc_like	164..403	CDD:304357	70/217 (32%)
CAMK1G	NP_065172.1	STKc_CaMKI_gamma	19..303	CDD:271068	70/217 (32%)
		Autoinhibitory domain. /evidence=ECO:0000250	277..317
		Calmodulin-binding. /evidence=ECO:0000250	297..318
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	325..352
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900