DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and dapk2a

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001116536.2	Gene:	dapk2a / 571352	ZFINID:	ZDB-GENE-080402-8	Length:	484	Species:	Danio rerio

Alignment Length:	267	Identity:	59/267 - (22%)
Similarity:	121/267 - (45%)	Gaps:	12/267 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 EAIQLYIETIEPVEHNTRTLIYRGQTRANRTKCTVKMVNK-QTQSNDRG----DTYMEAEVLRQL 202
            :.::.:.|..|.:......::.:.:.:::......|.:.| |:.::.||    :...|..:|:|:
Zfish     7 QQVEDFFEIGEELGSGQFAIVKQCREKSSGRDFAAKFIKKRQSNASRRGVLREEIEREVNILQQI 71

  Fly   203 QSHPNIIELMYTVEDERYMYTVLEHLD-CNMQKVIQKRGILSEADARSVMRCTVSALAHMHQLQV 266
            . ||||:.|....|::..:..:||.:. ..:...:.::..|||.:|...::..:..:.::|...:
Zfish    72 H-HPNIVMLHDVFENKTDVVLILELVSGGELFDFLAQKESLSEEEATQFIKQILEGVHYLHSRNI 135

  Fly   267 IHRDIKPENLLVCSSSGKWNFKMVKVANFDLA-TYYRGSKLYVRCGTPCYMAPEMIAMSGYDYQV 330
            .|.|:||||:::...:..  ...:|:.:|.|| ....|.:.....|||.::|||::.......:.
Zfish   136 AHFDLKPENIMLLDKNAP--LPRIKLIDFGLAHKIAEGVEFKNIFGTPEFVAPEIVNYEPLGLEA 198

  Fly   331 DSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPS 395
            |.||:||..:.:|.|..||....|  ::....|.:....:..:.....|..|...|..||..|..
Zfish   199 DMWSVGVITYILLSGASPFLGETK--QDTLGNISAMNYEFDDEFFGHTSELAKNFIRQLLEKDTK 261

  Fly   396 YRVPIAE 402
            .|:.|.:
Zfish   262 KRLTIQD 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	57/246 (23%)
		PKc_like	164..403	CDD:304357	57/246 (23%)
dapk2a	NP_001116536.2	PKc_like	7..275	CDD:304357	59/267 (22%)
dapk2a	NP_001116536.2	S_TKc	13..275	CDD:214567	59/261 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900