DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and mylk3

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001099057.1	Gene:	mylk3 / 561635	ZFINID:	ZDB-GENE-030131-3497	Length:	715	Species:	Danio rerio

Alignment Length:	339	Identity:	87/339 - (25%)
Similarity:	150/339 - (44%)	Gaps:	36/339 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 ETDIVICCCKNEEIICVKYSINKDFQRMVDSCKRWGQHHL---DSGTLESMKSHDLPEAIQLYIE 150
            |:|.::.|..:.:    ..|:::|.:......::.....|   ||..|.:...|.:..|.|:.|.
Zfish   339 ESDKIMICAVSPQ----NTSLDEDEKSKAAPLRKVESTLLIIDDSPPLPAPFDHRIVSAKQVPIN 399

  Fly   151 T---IEPVEHNTRTLIYRGQTRANRTKC---------TVKMVNKQTQSNDRGDTYMEAEVLRQLQ 203
            :   :.|||      :..|.......||         ..|:: |.....:|.:...|..|:.||
Zfish   400 SYYAVNPVE------VLGGGRFGQVHKCAELSSGLTLAAKII-KVRGMKERDEVKNEIGVMNQL- 456

  Fly   204 SHPNIIELMYTVEDERYMYTVLEHLDCN--MQKVIQKRGILSEADARSVMRCTVSALAHMHQLQV 266
            :|.|:|:|....|....:..::|:::..  .:::|.:...|:|.||....|.....:.::||..:
Zfish   457 NHVNLIQLYDAFESRTNLTLIMEYVEGGELFERIIDESYQLTELDAIVFTRQICEGVQYLHQQYI 521

  Fly   267 IHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYR-GSKLYVRCGTPCYMAPEMIAMSGYDYQV 330
            :|.|:||||:|..:|:|    ..:|:.:|.||..|| ..||.|..|||.::|||::......:..
Zfish   522 LHLDLKPENILCVNSTG----NQIKIIDFGLARKYRPREKLKVNFGTPEFLAPEVVNYDFVSFPT 582

  Fly   331 DSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPS 395
            |.||:||..:.:|.|..||..  .|..|....|:.....:..:....:|.||...|..||||...
Zfish   583 DMWSVGVITYMLLSGLSPFMG--DNDAETMNNILHAKWEFDTEAFENVSEEAKDFISSLLVSAKC 645

  Fly   396 YRVPIAELDKFQFL 409
            .|:..:...|..:|
Zfish   646 SRLSASGCMKHSWL 659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711	3/18 (17%)
		S_TKc	164..409	CDD:214567	70/256 (27%)
		PKc_like	164..403	CDD:304357	69/250 (28%)
mylk3	NP_001099057.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	67..114
		STKc_MLCK3	399..659	CDD:271094	73/273 (27%)
		S_TKc	407..659	CDD:214567	72/265 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900