DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and camk4

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001017607.1	Gene:	camk4 / 550270	ZFINID:	ZDB-GENE-050417-76	Length:	364	Species:	Danio rerio

Alignment Length:	275	Identity:	82/275 - (29%)
Similarity:	134/275 - (48%)	Gaps:	28/275 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 LESMKSHDLPEAIQLYIETIEPVEHNTRTLIYRGQTRANRTKCTVKMVNKQTQSNDRGDTYMEAE 197
            ::..|...|.:..:|..|    :.....:::||.:.:..:....|||:.|..   |:.....|..
Zfish    17 IDGSKKETLADFYELESE----LGRGATSVVYRCRQKGTQKHYAVKMLKKTV---DKKIVRTEIG 74

  Fly   198 VLRQLQSHPNIIELMYTVEDERYMYTVLEHLDCN--MQKVIQKRGILSEADARSVMRCTVSALAH 260
            ||.:| ||||||:|....|....:..|||.:...  ..:|::| |..||.||...::..:.|:|:
Zfish    75 VLLRL-SHPNIIKLKEIFETPAEISLVLELVTGGELFDRVVEK-GYYSERDAADAVKQVLEAVAY 137

  Fly   261 MHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGSKLY-------VRCGTPCYMAP 318
            :|:..|:|||:||||||..:|:..   ..:|:|:|.|      ||:.       ..||||.|.||
Zfish   138 LHENGVVHRDLKPENLLYATSAPD---APLKIADFGL------SKIVDDQVTMKTVCGTPGYCAP 193

  Fly   319 EMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEAT 383
            |::....|..:||.||:||..:.:|||..||... :..:.::..|::....:.......:|..|.
Zfish   194 EILRGCAYGPEVDMWSVGVITYILLCGFEPFFDD-RGDQYMFKRILNCEYEFVSPWWDNVSLNAK 257

  Fly   384 QLIDGLLVSDPSYRV 398
            .|:..|:|.||..|:
Zfish   258 DLVKKLIVQDPKKRL 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	78/244 (32%)
		PKc_like	164..403	CDD:304357	78/244 (32%)
camk4	NP_001017607.1	STKc_CaMKIV	25..318	CDD:270987	81/267 (30%)
camk4	NP_001017607.1	Pkinase	29..283	CDD:278497	80/263 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900