DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and stk17b

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_956829.1	Gene:	stk17b / 393507	ZFINID:	ZDB-GENE-040426-1499	Length:	354	Species:	Danio rerio

Alignment Length:	299	Identity:	73/299 - (24%)
Similarity:	128/299 - (42%)	Gaps:	28/299 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 QRMVDSCKRWGQHHLDSGTLESMKSHDLPEAIQLYIETIEPVEHNTRTLIYRGQTRANRTKCTVK 178
            :|.:||  |.|    .|..|..:.||...:.:....:..:.:......::.|...:........|
Zfish     3 RRRLDS--RSG----SSALLSEIHSHIHTDPLDTLFDIGKELGRGKFAVVKRCVEKTTGKVFAAK 61

  Fly   179 MVNKQTQSND-RGDTYMEAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHL-------DCNMQKV 235
            .:.|:.:..| |.|...|..||...:::|.::.|....|.:..:..:||..       .|...:
Zfish    62 FIKKRRRGRDCRADVIHEIAVLEAAKNNPRVVNLNAVYETDYDLVLMLEFAAGGEIFNHCVSDE- 125

  Fly   236 IQKRGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKVANFDLATY 300
                 :|.|.....::|..:..:..:||..|:|.|:||:|:|:.|.|...:   :|:.:|.||..
Zfish   126 -----LLPEGQITRLIRQMLEGIHLLHQSSVVHLDLKPQNILLTSLSPLGD---IKIVDFGLARR 182

  Fly   301 YRGSKLYVR--CGTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAI 363
            . ||...:|  .|||.|:|||::.........|.||:||..:.::.|:.|||.  .:.:|.:..:
Zfish   183 L-GSAGELREILGTPEYVAPEILNYEPITTATDLWSVGVITYMLVTGESPFAG--DDKQETFLNV 244

  Fly   364 MSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAE 402
            ......|.::..|.:|..|...|..|||..|..|...|:
Zfish   245 SQVNVEYSRETFSRVSELAVDFIRKLLVKAPEDRPSAAD 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	64/249 (26%)
		PKc_like	164..403	CDD:304357	64/249 (26%)
stk17b	NP_956829.1	STKc_DRAK2	24..290	CDD:271100	64/272 (24%)
stk17b	NP_956829.1	S_TKc	32..290	CDD:214567	64/264 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900