DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and triob

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_009290354.2	Gene:	triob / 368847	ZFINID:	ZDB-GENE-030616-399	Length:	3023	Species:	Danio rerio

Alignment Length:	307	Identity:	84/307 - (27%)
Similarity:	131/307 - (42%)	Gaps:	50/307 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 DSGTLESMKSHDLPEAI----------------------QLYIETIEPVEHNTRTLIYRG----- 166
            ||||...:.|:|:....                      .||.|.:|         :.||
Zfish  2680 DSGTYTCIASNDVGSVTSSAYLRVLGTSCDGILWKDNFESLYTEVME---------LGRGRFAVT 2735

  Fly   167 ---QTRANRTKCTVKMVNKQTQSNDRGDTYMEAEVLRQLQSHPNIIELMYTVEDERYMYTVLEHL 228
               :.|.:|.....|:|||:...  |.....|..||:.|| ||:::.|:.|.|.......:||..
Zfish  2736 KWCEQRGSRRSVAAKLVNKKLMR--REQVVQELGVLQCLQ-HPHLVGLLDTYETPASYVLILEIA 2797

  Fly   229 D-CNMQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMVKV 292
            | ..:...|...|.|:|......:|..:.||.::|..::.|.|:||||:|:..:|.|   .:||:
Zfish  2798 DQGRILDYIVSWGNLTEEKVSLYLRDVLEALHYLHACRIAHLDLKPENVLIEQTSAK---PLVKL 2859

  Fly   293 ANF-DLATYYRGSKLYVRCGTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNS 356
            |:| |.|.......::...|:|.:.|||::.........|.|||||..:.||.|..||..  ::.
Zfish  2860 ADFGDAAHLSNTPYIHPLLGSPEFSAPELVLGEPAALASDLWSLGVLAYVMLSGASPFLD--ESV 2922

  Fly   357 KEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAEL 403
            :|....|.....::|:|....:|..|...|..||..:|..| |.|::
Zfish  2923 EETCLNICRIDFSFPEDYFHGVSQAARDFICMLLQGEPCRR-PSAQV 2968

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	74/250 (30%)
		PKc_like	164..403	CDD:304357	74/248 (30%)
triob	XP_009290354.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900