DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and sqa

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001260832.1	Gene:	sqa / 36002	FlyBaseID:	FBgn0259678	Length:	888	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	73/250 - (29%)
Similarity:	122/250 - (48%)	Gaps:	11/250 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 IYRGQTRANRTKCTVKMVNKQTQSNDRGDTYMEAEVLRQLQSHPNIIELMYTVEDERYMYTVLEH 227
            :|:.:.:||..:...|.| ...:..|:.:...|.|::..||.| .||:|....|.::.|..|||.
  Fly    48 VYKCRDKANGLQLAAKFV-PIPKREDKRNVEREVEIMNSLQHH-LIIQLYAAYEYQKMMCVVLEL 110

  Fly   228 LDCN--MQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWNFKMV 290
            ::..  ..:|:....:|:|...|..:|....|:|.:|...::|.|:||||:||.:..|    ..:
  Fly   111 IEGGELFDRVVDDEFVLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENILVLTQKG----NRI 171

  Fly   291 KVANFDLATYYRGSK-LYVRCGTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACK 354
            |:.:|.||..:...| |.|..|||.::|||::......|..|.||:||..:.::.|..||..  :
  Fly   172 KIIDFGLARKFDPDKRLRVLFGTPEFVAPEVVNFDCISYGTDMWSVGVICYVLISGLSPFMG--E 234

  Fly   355 NSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAELDKFQFL 409
            |..|..:.:......:..:..:.:|||....|..||..|.|.|:..||..|.::|
  Fly   235 NDIETMSNVTIAKYDFEDECFNGISPECLDFIAKLLAKDLSTRMTAAECMKHKWL 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	72/247 (29%)
		PKc_like	164..403	CDD:304357	70/241 (29%)
sqa	NP_001260832.1	S_TKc	34..289	CDD:214567	72/248 (29%)
sqa	NP_001260832.1	STKc_MLCK	40..289	CDD:271005	72/248 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900