DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and kin-33

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001367716.1	Gene:	kin-33 / 178549	WormBaseID:	WBGene00017083	Length:	337	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	65/215 - (30%)
Similarity:	106/215 - (49%)	Gaps:	21/215 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 HPNIIELMYTVEDERYMYTVLEHLD-CNMQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIH 268
            |.|:|..:.......:.:.::|:.| .::...|.....|:.:.|....:..::.|.::|...|.|
Worm    79 HENVIRFLSIRTMPEHYFLIMEYADGGDLFDKISSEYRLTSSQAHGYFKQLIAGLRYIHSKGVTH 143

  Fly   269 RDIKPENLLVCSSSGKWNFKMVKVANFDLATYY--RG--SKLYVRCGTPCYMAPEMIAMSGYDYQ 329
            ||||||||::..:.      ::|:.:|.|.|.:  :|  |.:..|||||.|.|||::.  |..|:
Worm   144 RDIKPENLMLTKAG------VLKITDFGLGTLHIIKGEESLMDTRCGTPQYAAPEVLV--GNQYR 200

  Fly   330 ---VDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLV 391
               ||.||.||.|..||.|..|:..||| |...|....:...| .:|..|.:......|:..:|.
Worm   201 GPPVDIWSAGVVLINMLTGHSPWKKACK-SDASYTRWFNDECT-ERDAWSDLGARVITLLCSILA 263

  Fly   392 SDPSYRVPIAELDK---FQF 408
            .:|::|.||..:::   |||
Worm   264 HNPTHRAPIELIEQDHWFQF 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	65/215 (30%)
		PKc_like	164..403	CDD:304357	62/205 (30%)
kin-33	NP_001367716.1	PKc_like	16..281	CDD:419665	62/211 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162445
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930