Protein Alignment CG10177 and zyg-8

DIOPT Version :9

• Sequence 1: NP_651150.1
• Gene: CG10177 / 42772
• FlyBaseID: FBgn0039083
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_499571.2
• Gene: zyg-8 / 176639
• WormBaseID: WBGene00006993
• Length: 802
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 131/558 - (23%)
• Similarity: 210/558 - (37%)
• Gaps: 184/558 - (32%)

  Fly    12 RVGP---PLHKKALRVCFLRNGDRHFKGVNLVISRAHFKDFPALLQGVTESLKRHVL-----LRS 68
            |:||   |...||.|:.|.||||::|||:...:.....|.    :|.:.|.|.:.|:     |..
 Worm   198 RIGPSGYPHLLKAKRLRFYRNGDQYFKGIQYALQSDRVKS----MQPLMEDLMKTVICDSTALPH 258

  Fly    69 AIAHFRRTDGS-HLTSLSCFRETDIVIC------------------------------------- 95
            .|.|....||: .:||:..|.:....:|
 Worm   259 GIRHIFTIDGAQRITSVDQFEDGGGYVCSSTDAFKPVDYSRAAEPSWRLTLANRYNRHLETKKLA 323

  Fly    96 ------CCKNEEII----------------CVKYSINKDFQRMVDSCKR--WGQHHLDSGTL--- 133
                  |.:|.:.:                ..::.:||...|..|...|  .....||||.:
 Worm   324 LSVVEPCHENTDFVFPRIIKVIRNGVKPRRISRHLLNKKTARSFDQVLRDLTFVVKLDSGAIRKL 388

  Fly   134 ---------------------------ESMKSHDLPEAIQLYIETIEPVEHNTRTLIYRGQTRAN 171
                                       |.|.:.||..|.:.:.........|.|. ..|..|..|
 Worm   389 FTLSGRPVLSLQDFFRDDDVFVAYGGNEKMAADDLLVASEEHKSVGSGTSSNMRR-TSRRSTMPN 452

  Fly   172 R---------------------------------------TKCTVKMVNKQTQSNDR-------- 189
            |                                       |....::::| |.::||
 Worm   453 RNESLRHDRSGSVIPDQDQQRLPPLLDEKFQLVRLIGDGNTAVVYEVIDK-TNNDDRKAMKVIAR 516

  Fly   190 ----GDTY---MEAEVLRQLQSHPNIIELM--YTVEDERY-------MYTVLEHLDCNMQKVIQK 238
                |..:   ||..:|::: .|..|::|.  :.|:|..|       |..:.|||     :::::
 Worm   517 ENVIGKEHLIEMELAILQKI-DHTFIVQLYDHWFVDDSYYLSLELIEMGDLFEHL-----RIVRR 575

  Fly   239 RGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSS-GKWNFKMVKVANFDLATYYR 302
               :.|.||..:|.|...||.::|:|.::|||:|.||||:.... |:..   ||:|:|.||....
 Worm   576 ---VPERDAVRMMTCLGQALEYIHELGIVHRDVKLENLLIVKDEFGELG---VKLADFGLAAEMP 634

  Fly   303 G--SKLYVRCGTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMS 365
            .  ..|...||||.|:|||::..:||..:||.|:.||.|:.:|.|..||.|:..:.:::::||||
 Worm   635 KDFGVLSTICGTPTYVAPEVLNKTGYGCKVDIWAAGVILYAILVGFPPFQSSDGSEQDLFSAIMS 699

  Fly   366 GGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAEL 403
            |..::|......:|.....||..|:.:||.:|....||
 Worm   700 GEFSFPSPSWDDVSWSVRHLIMCLIHTDPFHRYSAGEL 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711	27/154 (18%)
		S_TKc	164..409	CDD:214567	84/306 (27%)
		PKc_like	164..403	CDD:304357	82/304 (27%)
zyg-8	NP_499571.2	DCX	206..298	CDD:214711	25/95 (26%)
		DCX	335..423	CDD:214711	11/87 (13%)
		STKc_DCKL	481..742	CDD:270997	80/270 (30%)
		S_TKc	482..743	CDD:214567	80/269 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.946395	Normalized mean entropy	S5828
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44167
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.910