DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and R06A10.4

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001380035.1	Gene:	R06A10.4 / 171688	WormBaseID:	WBGene00019911	Length:	391	Species:	Caenorhabditis elegans

Alignment Length:	265	Identity:	77/265 - (29%)
Similarity:	131/265 - (49%)	Gaps:	19/265 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 ETIEPVEHNTRTLIYRGQTRANRTKCTVKMVNKQTQSNDRGDTYMEAEVLRQLQSHPNIIELMYT 214
            |.:..|...:.:.:.|.|.|..|....||:||     .|.|....|..:|.:| |||.:|.|...
Worm    72 EVLAVVGKGSFSQVLRVQHRVTRKYFAVKVVN-----GDCGAVNNELNILSRL-SHPFVIRLEEV 130

  Fly   215 VEDERYMYTVLEHLD-CNMQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLV 278
            .:....::.|::... ..|...:..:|..||.:||:.::..::.|.::|.::|.|||:||||||.
Worm   131 FKSSSKLFIVMQMASGGEMYDRVVAKGRYSEEEARNALKMLLTGLTYLHSIRVTHRDLKPENLLY 195

  Fly   279 CSSSGKWNFKMVKVANFDLATYYRGSK----LYVRCGTPCYMAPEMIAMSGYDYQVDSWSLGVTL 339
            ..|..:   ..:.:.:|.||  |:.:|    :...||||.|:|||::....|..:||.|::||..
Worm   196 ADSRPE---ARLLITDFGLA--YQATKPNETMTETCGTPEYIAPELLLRVPYTQKVDMWAVGVIA 255

  Fly   340 FYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAELD 404
            :.::.|.|||...|::  .:|..|::....|.....| .|..|.|.:|.||.::...|:..:...
Worm   256 YILMSGIMPFDDDCRS--RLYTHIITANYVYYPQFWS-GSELAKQFVDSLLETNSVERLSSSAAM 317

  Fly   405 KFQFL 409
            |.::|
Worm   318 KHEWL 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	74/249 (30%)
		PKc_like	164..403	CDD:304357	73/243 (30%)
R06A10.4	NP_001380035.1	STKc_PSKH1	69..322	CDD:270989	76/263 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900