DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and Stk17b

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_596883.1	Gene:	Stk17b / 170904	RGDID:	620457	Length:	371	Species:	Rattus norvegicus

Alignment Length:	273	Identity:	69/273 - (25%)
Similarity:	125/273 - (45%)	Gaps:	41/273 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 TIEPVEHNTRTLIYRGQ--------TRANRTKCTVKMVNKQTQSND-RGDTYMEAEVLRQLQSHP 206
            |:.|.|      :.||:        :::...:...|.:.|:.:..| |.:...|..||...:|.|
  Rat    33 TLTPKE------LGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELARSCP 91

  Fly   207 NIIELMYTVEDERYMYTVLEH------LDCNMQKVIQKRGILSEADARSVMRCTVSALAHMHQLQ 265
            ::|.|....|....:..|||:      .:..:.::.:   ::||.|...:::..:..:.::||..
  Rat    92 HVINLHEVYETATEIILVLEYAAGGEIFNLCLPELAE---MVSENDVIRLIKQILEGVHYLHQNN 153

  Fly   266 VIHRDIKPENLLVCSSSGKWNFKMV------KVANFDLATYYRGSKLYVRCGTPCYMAPEMIAMS 324
            ::|.|:||:|:|:.|.....:.|:|      |:.|        .|:|....|||.|:|||::...
  Rat   154 IVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGN--------ASELREIMGTPEYLAPEILNYD 210

  Fly   325 GYDYQVDSWSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGL 389
            ......|.|::|:..:.:|....||..  ::::|.|..|......|.::|.|.:|..||..|..|
  Rat   211 PITTATDMWNIGIIAYMLLTHTSPFVG--EDNQETYLNISQVNVDYSEEMFSSVSQLATDFIQSL 273

  Fly   390 LVSDPSYRVPIAE 402
            ||.:|..| |.||
  Rat   274 LVKNPEKR-PTAE 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711
		S_TKc	164..409	CDD:214567	66/260 (25%)
		PKc_like	164..403	CDD:304357	66/260 (25%)
Stk17b	NP_596883.1	STKc_DRAK2	24..293	CDD:271100	69/273 (25%)
Stk17b	NP_596883.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	308..345
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900