Protein Alignment CG10177 and DCLK2

DIOPT Version :9

• Sequence 1: NP_651150.1
• Gene: CG10177 / 42772
• FlyBaseID: FBgn0039083
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001035351.4
• Gene: DCLK2 / 166614
• HGNCID: 19002
• Length: 783
• Species: Homo sapiens
• Alignment Length: 643
• Identity: 145/643 - (22%)
• Similarity: 219/643 - (34%)
• Gaps: 279/643 - (43%)

  Fly     5 STSLGSRRVGP--------PLH------------------KKALRVCFLRNGDRHFKGVNLVISR 43
            |:|.||...||        |.|                  |||.:..|.|||||:|||:...||.
Human    29 SSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVFAISS 93

  Fly    44 AHFKDFPALLQGVTESLKRHVLLRSAIAHFRRTDGSH-LTSLSCFRETDIVICCCKNEEIICVKY 107
            ..|:.|.|||..:|.||..:|.|...:......|||. :|||....|.:..: |..||....|.|
Human    94 DRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYV-CASNEPFRKVDY 157

  Fly   108 SIN------------------------------KDF--QRMVDSCKRWGQHHLDSGT-------- 132
            :.|                              |||  .::|...:        ||.
Human   158 TKNINPNWSVNIKGGTSRALAAASSVKSEVKESKDFIKPKLVTVIR--------SGVKPRKAVRI 214

  Fly   133 -LESMKSH-------DLPEAIQL--------------------------------------YIET 151
             |....:|       |:.|||:|                                      |.:.
Human   215 LLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQD 279

  Fly   152 IEPVEHN---------TRTLIYR-------GQTRANRTKCTVKM--------------VN----- 181
            ...::|:         :|:...:       |.:|.:::..:||.              ||
Human   280 DFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVKRGGHYSSAYSTAKSPVNGTPSS 344

  Fly   182 -----KQTQSN------------------------------------------------------ 187
                 |.|:|:
Human   345 QLSTPKSTKSSSSSPTSPGSFRGLKQISAHGRSSSNVNGGPELDRCISPEGVNGNRCSESSTLLE 409

  Fly   188 --------------------DR-----------------GDTYM---EAEVLRQLQSHPNIIELM 212
                                ||                 |..::   |..:||::: |||||.|:
Human   410 KYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVK-HPNIIMLV 473

  Fly   213 YTVEDERYMYTVLEHLDCNMQKVIQKRGIL----------SEADARSVMRCTVSALAHMHQLQVI 267
            ..:|....::.|:|         :.|.|.|          :|.|..:::....:||.::|.|.::
Human   474 EEMETATELFLVME---------LVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIV 529

  Fly   268 HRDIKPENLLVCSSSGKWNFKMVKVANFDLATYYRGSKLYVRCGTPCYMAPEMIAMSGYDYQVDS 332
            ||||||||||||....  ..|.:|:.:|.|||...| .||..||||.|:|||:||.:||..:||.
Human   530 HRDIKPENLLVCEYPD--GTKSLKLGDFGLATVVEG-PLYTVCGTPTYVAPEIIAETGYGLKVDI 591

  Fly   333 WSLGVTLFYMLCGKMPFASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLL 390
            |:.||..:.:|||..||.|.....::::..|::|...:|......::..|.:||..:|
Human   592 WAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQML 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711	36/108 (33%)
		S_TKc	164..409	CDD:214567	84/362 (23%)
		PKc_like	164..403	CDD:304357	84/362 (23%)
DCLK2	NP_001035351.4	DCX	67..157	CDD:214711	35/90 (39%)
		DCX	192..280	CDD:214711	13/95 (14%)
		STKc_DCKL2	409..667	CDD:271086	75/254 (30%)
		S_TKc	411..668	CDD:214567	75/252 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770