DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10177 and UHMK1

DIOPT Version :9

Sequence 1:NP_651150.1 Gene:CG10177 / 42772 FlyBaseID:FBgn0039083 Length:411 Species:Drosophila melanogaster
Sequence 2:NP_787062.1 Gene:UHMK1 / 127933 HGNCID:19683 Length:419 Species:Homo sapiens


Alignment Length:258 Identity:67/258 - (25%)
Similarity:99/258 - (38%) Gaps:85/258 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   195 EAEVLRQLQSHPNIIEL--MYTVE-------------------DERYMYTVLEHLDCNMQKVIQK 238
            |...|.|||.|.||:.|  ::|:.                   .|..:|:  .|..|:|..:   
Human    76 ERAALEQLQGHRNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVSELLLYS--SHQGCSMWMI--- 135

  Fly   239 RGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGKWN-----FKMVKVANFDLA 298
                 :..||.|:    .|||.:|....:|.|:||.|:|       |:     ||::   :|.| 
Human   136 -----QHCARDVL----EALAFLHHEGYVHADLKPRNIL-------WSAENECFKLI---DFGL- 180

  Fly   299 TYYRGSKLYVRCGTPCYMAPE-----MIAMSGYDYQ------VDSWSLGVTLFYMLCG-KMPFAS 351
            ::..|::......|..|.|||     .:|.:|....      ||.||||:.|..|..| |:....
Human   181 SFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGMKLKHTV 245

  Fly   352 ACK----NSKEIY-------AAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYRVPIAEL 403
            ..:    ||..|.       |.:.:..|.|          ....||..:|..|||.|:| ||:
Human   246 RSQEWKANSSAIIDHIFASKAVVNAAIPAY----------HLRDLIKSMLHDDPSRRIP-AEM 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10177NP_651150.1 DCX 18..108 CDD:214711
S_TKc 164..409 CDD:214567 67/258 (26%)
PKc_like 164..403 CDD:304357 66/256 (26%)
UHMK1NP_787062.1 STKc_KIS 22..308 CDD:270922 67/258 (26%)
RRM_SF 318..405 CDD:418427
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0032
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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