DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10177 and dclk3

DIOPT Version :9

Sequence 1:	NP_651150.1	Gene:	CG10177 / 42772	FlyBaseID:	FBgn0039083	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_017950468.2	Gene:	dclk3 / 100493379	XenbaseID:	XB-GENE-983282	Length:	793	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	88/308 - (28%)
Similarity:	139/308 - (45%)	Gaps:	55/308 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 CCCKNEEIICVKYSINKDFQ----RMVDSCKRWGQHHLDSGTLESMKSHDLPEAIQLYIETIEPV 155
            ||.|....|...|.|.:...    .:|..|:.|.::                   |.|
Frog   489 CCIKTSRDIESYYEIGRTIGDGNFAVVKVCRPWNEN-------------------QEY------- 527

  Fly   156 EHNTRTLIYRGQTRANRTKCTVKMVNKQTQSNDRGDTYMEAEVLRQLQSHPNIIELMYTVEDERY 220
                                .:|:::|............|..:::.| |||||::|....|.|:.
Frog   528 --------------------AMKIIDKSKLRGKEDIIENEVRIIKHL-SHPNIVKLFSDYETEKE 571

  Fly   221 MYTVLEHL-DCNMQKVIQKRGILSEADARSVMRCTVSALAHMHQLQVIHRDIKPENLLVCSSSGK 284
            :|.:||:: ..::..||.:....:|.||..::.....||.::|...::|||:|||||||..:..
Frog   572 IYLILEYIRGGDLFDVITESIKFTEHDAALMLIDLCEALKYIHSKHIVHRDLKPENLLVQHNPD- 635

  Fly   285 WNFKMVKVANFDLATYYRGSKLYVRCGTPCYMAPEMIAMSGYDYQVDSWSLGVTLFYMLCGKMPF 349
             ..|.:|:|:|.||.|..| .::..||||.|:|||:::..||..:||.|:.||.|:.:|||..||
Frog   636 -GSKSLKLADFGLAIYATG-PIFTVCGTPTYVAPEILSEKGYGLKVDMWATGVILYILLCGFPPF 698

  Fly   350 ASACKNSKEIYAAIMSGGPTYPKDMESVMSPEATQLIDGLLVSDPSYR 397
            .|..:|.:|::..|.||...:.......:|.|...||..|||.:|..|
Frog   699 RSPDRNQEELFQIIQSGEYEFLPPYWDHISEEVKDLISKLLVLNPEIR 746

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10177	NP_651150.1	DCX	18..108	CDD:214711	4/12 (33%)
		S_TKc	164..409	CDD:214567	77/235 (33%)
		PKc_like	164..403	CDD:304357	77/235 (33%)
dclk3	XP_017950468.2	DCX_DCLK3	87..171	CDD:340528
dclk3	XP_017950468.2	STKc_DCKL3	500..757	CDD:271087	84/297 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910