Protein Alignment Irk2 and Kcnj11

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_112648.2
• Gene: Kcnj11 / 83535
• RGDID: 69247
• Length: 390
• Species: Rattus norvegicus
• Alignment Length: 376
• Identity: 168/376 - (44%)
• Similarity: 235/376 - (62%)
• Gaps: 35/376 - (9%)

  Fly    51 PQSYPITIVPNRPTSYYGLSQNGKPFPRQPSCRSRNFRPGSMRRVRRRAVFKNGDCNVVQKHLQR 115
            |:.|.:|.:...||              :|..|:        |..|.|.|.|.|:|||..|:: |
  Rat     9 PEEYVLTRLAEDPT--------------EPRYRT--------RERRARFVSKKGNCNVAHKNI-R 50

  Fly   116 RRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIYTHGDLEEPHLPENQEESGWA 180
            .:.|||||::||:||.:|..|||.|.:||:.|||.||::||||.:.||||.       ..|....
  Rat    51 EQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLA-------PGEGTNV 108

  Fly   181 PCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQSIYGVMSSAFMAGIVFAKMTR 245
            |||::|..|:|.||||||.|.|||:|.|..:.|||.||.::..|:|.|:|.:|.|.|.:|.|..:
  Rat   109 PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQ 173

  Fly   246 AKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQLIRTKSTKEGEVMTQYFTEL 310
            |.:||:||:|||||||..|.|.|..|.||||:|||.||.|.:..|::|..::.||||:..:..::
  Rat   174 AHRRAETLIFSKHAVITLRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDI 238

  Fly   311 EIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDM--LQDKFEIVVILEGTVESTGQSTQARS 373
            .:.....|:.:|.:.|::|.|.||.|||||:|..:|:  .|| .||:|||||.||:||.:||||:
  Rat   239 PMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQD-LEIIVILEGVVETTGITTQART 302

  Fly   374 SYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPLCSARELNE 424
            ||:..|||||.||.|:|.  ::...|.:||::|..|.:|.||||:||:|:|
  Rat   303 SYLADEILWGQRFVPIVA--EEDGRYSVDYSKFGNTVKVPTPLCTARQLDE 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	158/327 (48%)
Kcnj11	NP_112648.2	IRK	36..356	CDD:279361	158/327 (48%)
		Selectivity filter. /evidence=ECO:0000250	130..135		3/4 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930