Protein Alignment Irk2 and kcnj12b

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_001335950.1
• Gene: kcnj12b / 795702
• ZFINID: ZDB-GENE-091118-79
• Length: 421
• Species: Danio rerio
• Alignment Length: 415
• Identity: 174/415 - (41%)
• Similarity: 245/415 - (59%)
• Gaps: 33/415 - (7%)

  Fly    48 ISNPQSYPITIVPNRPTSYYGLSQ-------NGKPFPRQPSCRSRNFRPGSMRRVRRRAVFKNGD 105
            :..|..|.|..........:|...       |||...|              |::|.|.|.|.|.
Zfish     3 VGKPHRYNIVSSSEEDVGRHGTMPALGNGFGNGKIQTR--------------RKLRSRFVNKTGQ 53

  Fly   106 CNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIYTHGDLEEPHL 170
            |||...|:..:..|:|.|::||.||.:|||..|.|:|:|::|||.|...:|||...|||||:|
Zfish    54 CNVSFAHMDEQSQRYLADIFTTCVDSRWRWMFLLFSLAFVISWLAFGFAFWLIALVHGDLEKP-- 116

  Fly   171 PENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQSIYGVMSSAFM 235
                 :..:.|||..::.|.:.||||:|||.|||||.|..:.|||.|:||:.||||.|.:..:||
Zfish   117 -----QENFTPCVMQVNSFVAAFLFSVETQTTIGYGFRCVTEECPLAVFMVVFQSIVGCIIDSFM 176

  Fly   236 AGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQLIRTKSTKEG 300
            .|.:.|||.|.|:||:|:|||.:|||..|||.|.||:|||::|||||:.|.||||||:.:.|:||
Zfish   177 IGAIMAKMARPKKRAETILFSHNAVISMRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRITEEG 241

  Fly   301 EVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDKFEIVVILEGTVEST 365
            |.:.....::.:|.|.....:|.:.|:.|.|:|:|.|||:.:|..|:....|||||||||.||:|
Zfish   242 EYIPLDQIDINVGYDQGLDRIFLVAPLTILHEINEESPLFGINQQDLETSDFEIVVILEGMVEAT 306

  Fly   366 GQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQV-DTPLCSARELNEIYKIQ 429
            ..:.|.||||:::||||||||:|||.  ::...|::||:.|::|.:| .||.|||::|.:...::
Zfish   307 AMTAQVRSSYLSSEILWGHRFEPVVF--EERNQYKVDYSHFHKTYEVPSTPRCSAKDLEDNKSLE 369

  Fly   430 EG--FRTPAETTFTMRQLSHNHSDQ 452
            .|  |....|..|..|.......|:
Zfish   370 SGANFCYENELAFISRDEEEQEEDR 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	159/336 (47%)
kcnj12b	XP_001335950.1	IRK_N	2..47	CDD:312087	10/57 (18%)
		IRK	48..367	CDD:307239	157/327 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	195	1.000	Domainoid score	I3095
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6393
orthoMCL	1	0.900	-	-		OOG6_101017
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X128
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.830