Protein Alignment Irk2 and kcnj11

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001034916.1
• Gene: kcnj11 / 664687
• ZFINID: ZDB-GENE-060308-2
• Length: 381
• Species: Danio rerio
• Alignment Length: 362
• Identity: 158/362 - (43%)
• Similarity: 232/362 - (64%)
• Gaps: 18/362 - (4%)

  Fly    96 RRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIY 160
            :.|.|.|||.|||...:: |.:.|||||::||:||.:|..||:.|.:||:.|||.|.:|||||.:
Zfish    32 KARFVAKNGTCNVAHTNI-REQGRFLQDVFTTLVDLKWLHTLVIFTMSFLCSWLLFGMIWWLIAF 95

  Fly   161 THGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQS 225
            .||||:       .:...:.|||:.|..|:|.||||||.|.|||:|.|..:.||..||.::..|:
Zfish    96 AHGDLD-------LKGEDFVPCVTDIHSFSSAFLFSIEVQVTIGFGGRMITEECVSAIVILILQN 153

  Fly   226 IYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQ 290
            |.|::.:|.|.|.:|.|..:|.:||:||:|||||||..|:..|..|||:||:|||.||.|.|..|
Zfish   154 IVGLVINAIMLGCIFMKTAQANRRAETLIFSKHAVITVRNNKLCFMFRLGDLRKSMIISATVHMQ 218

  Fly   291 LIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDKFEIV 355
            ::|...|.|||::.....::::......:.:|.:.|::|.|.||:|||||:|:|.|:|.:..|::
Zfish   219 VVRKTVTSEGEMVPLDQIDIQMDNPVGTNSIFLVSPLIISHTIDKNSPLYDLSADDLLHEDIEVI 283

  Fly   356 VILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPLCSAR 420
            |:|||.||:||.:||||:||::.||||||||.|.|  :::...|.:||::|..|.:|.||..|||
Zfish   284 VVLEGVVETTGITTQARTSYLSEEILWGHRFVPTV--SEEDGMYAVDYSKFGNTVKVATPNSSAR 346

  Fly   421 ELNEI-----YKIQEGFRTPAETTFTMRQLSHNHSDQ 452
            .|.|.     :|:||   |........|::.|.::.:
Zfish   347 TLEEAGGMERFKLQE---TSGACAAVRRRVKHPNTKE 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	154/338 (46%)
kcnj11	NP_001034916.1	IRK	36..362	CDD:279361	154/338 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.930