Protein Alignment Irk2 and kcnj5

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_700619.4
• Gene: kcnj5 / 571888
• ZFINID: ZDB-GENE-120215-97
• Length: 425
• Species: Danio rerio
• Alignment Length: 332
• Identity: 151/332 - (45%)
• Similarity: 224/332 - (67%)
• Gaps: 9/332 - (2%)

  Fly    92 MRRVRRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWW 156
            :::.|:|.|.|:|.|||...:: :...|:|.|::||:||.:||.:...|.|.::::||||..:||
Zfish    47 VKKPRQRYVQKDGKCNVHHGNV-KETYRYLSDLFTTLVDLRWRLSFFIFTLVYVVNWLFFGFLWW 110

  Fly   157 LIIYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMM 221
            ||....|||      .:.:|.||.|||..::.|.|.|||||||:.|||||.|..:.:|||.|.::
Zfish   111 LIALIRGDL------LHSDEEGWTPCVENLNSFVSAFLFSIETETTIGYGYRVITEKCPEGIILL 169

  Fly   222 CFQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAG 286
            ..|:|.|.:.:|.|.|.:|.|:::.|.||:||:||.:|||..||..:.|||||||:|.|||:.|.
Zfish   170 MVQAILGSIVNAMMVGCMFVKISQPKNRAETLMFSHNAVISVRDNKMCLMFRVGDLRNSHIVEAS 234

  Fly   287 VRAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDK 351
            :||:|||::.|||||.:....|::.||.|.....||.:.|::|.|:|:|.||.:.::...|.:::
Zfish   235 IRAKLIRSQQTKEGEFIPLNQTDINIGFDTGDDRLFLVSPLIISHEINEKSPFWEMSRAQMEKEE 299

  Fly   352 FEIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPL 416
            |||||||||.||:||.:.||||||:::|:|||.||.||:...|..  ||:||..|::..:.:||.
Zfish   300 FEIVVILEGMVEATGMTCQARSSYLDSEVLWGFRFTPVLSLEKGF--YEVDYNNFHDIYETNTPT 362

  Fly   417 CSARELN 423
            |||:||:
Zfish   363 CSAKELS 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	149/324 (46%)
kcnj5	XP_700619.4	IRK	55..368	CDD:279361	147/321 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580677
Domainoid	1	1.000	195	1.000	Domainoid score	I3095
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	366	1.000	Inparanoid score	I2116
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	1	1.000	-	-		FOG0000937
OrthoInspector	1	1.000	-	-		mtm6393
orthoMCL	1	0.900	-	-		OOG6_101017
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X128
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.810