Protein Alignment Irk2 and kcnj6

DIOPT Version :10

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_073770397.1
• Gene: kcnj6 / 569498
• ZFINID: ZDB-GENE-120327-2
• Length: 412
• Species: Danio rerio
• Alignment Length: 356
• Identity: 164/356 - (46%)
• Similarity: 237/356 - (66%)
• Gaps: 17/356 - (4%)

  Fly    78 RQPSC--RSRNFRPGSMRRVRR------RAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWR 134
            |||..  ::|:..|..::...|      |.|.|:|.|||...:: |...|:|.|::||:||.:||
Zfish    22 RQPKLPKQARDDIPKPLQERERAKQKTQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWR 85

  Fly   135 WTLLAFALSFILSWLFFALIWWLIIYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIET 199
            :.|..|.|.:.::||||..:||||.|..||||  |:.:||    |.|||:.::||.|.|||||||
Zfish    86 FNLFIFVLVYTVTWLFFGFMWWLIAYIRGDLE--HIGDNQ----WTPCVNNLNGFVSAFLFSIET 144

  Fly   200 QHTIGYGVRTTSPECPEAIFMMCFQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQR 264
            :.|||||.|..:.:|||.|.::..||:.|.:.:|||.|.:|.|:::.|:||:||:||.:|||..|
Zfish   145 ETTIGYGHRVITDKCPEGIVLLLVQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTNAVISMR 209

  Fly   265 DGTLSLMFRVGDMRKSHIIGAGVRAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVI 329
            ||.|.|||||||:|.|||:.|.:||:||::|.|||||.:....|::.:|.|.....||.:.|::|
Zfish   210 DGRLCLMFRVGDLRNSHIVEASIRAKLIKSKQTKEGEFIPLNQTDINVGYDTGDDRLFLVSPLII 274

  Fly   330 EHKIDENSPLYNLNATDMLQDKFEIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNK 394
            .|:|:::||.:.::...|.:::.||||||||.||:||.:.||||||:.:||.||:||.||:....
Zfish   275 CHEINQHSPFWEISREHMAKEELEIVVILEGMVEATGMTCQARSSYVASEIKWGYRFTPVLTLED 339

  Fly   395 DLQAYEIDYARFNETTQVDTPLCSARELNEI 425
            ..  ||:||..|:|..:.:||.||||||.|:
Zfish   340 GF--YEVDYNSFHEIYETNTPSCSARELAEM 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..246	CDD:460023	68/145 (47%)
		IRK_C	253..424	CDD:465439	84/170 (49%)
kcnj6	XP_073770397.1	None