Protein Alignment Irk2 and kcnj2a

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001318145.1
• Gene: kcnj2a / 564522
• ZFINID: ZDB-GENE-120319-1
• Length: 427
• Species: Danio rerio
• Alignment Length: 390
• Identity: 169/390 - (43%)
• Similarity: 241/390 - (61%)
• Gaps: 32/390 - (8%)

  Fly    36 AIEADPDSLDSVISNPQSYPITIVPNRPTSYYGLSQNGKPFPRQPSCRSRNFRPGSMRRVRRRAV 100
            ::.|:..|:.|...:........|||.    ||   |||.            :..:..:.:.|.|
Zfish     3 SVRANRYSIVSSEEDGMKLATAAVPNG----YG---NGKS------------KVHTRHQTQSRFV 48

  Fly   101 FKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIYTHGDL 165
            .|:|.|||...::..:..|:|.|::||.||.:|||..:.|.|:|:||||||..|:||:...||||
Zfish    49 KKDGHCNVQFINVSEKSQRYLADIFTTCVDIRWRWMFVIFCLAFLLSWLFFGCIFWLVAIFHGDL 113

  Fly   166 EEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQSIYGVM 230
                      |:....|||.:..||:.||||||||.|||||.|..:.|||.|:||:.||||.|.:
Zfish   114 ----------ENNGHKCVSNVSSFTAAFLFSIETQTTIGYGYRYVTDECPIAVFMVVFQSIVGCI 168

  Fly   231 SSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQLIRTK 295
            ..||:.|.|.|||.:.|:|.:||:||.:|.:..||..|.||:|||::||||::.|.|||||:|::
Zfish   169 IDAFIIGAVMAKMAKPKKRNETLVFSHNATVAMRDNKLCLMWRVGNLRKSHLVEAHVRAQLLRSR 233

  Fly   296 STKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDKFEIVVILEG 360
            :|.|||.:.....::::|.|.....:|.:.|:.|.|:|||:||.|:::..:|....|||||||||
Zfish   234 TTAEGEFIPLDQMDIDVGFDSGIDRIFLVSPITIVHEIDEDSPFYDMSKQEMENSDFEIVVILEG 298

  Fly   361 TVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQV-DTPLCSARELNE 424
            .||:|..:||.||||:..||||.|||:||:...|:.  |::||:||::|.:| .|||||||:|.|
Zfish   299 MVEATAMTTQCRSSYVANEILWAHRFEPVLFEEKNY--YKVDYSRFHKTYEVPSTPLCSARDLAE 361

  Fly   425  424
            Zfish   362  361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	157/326 (48%)
kcnj2a	NP_001318145.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	195	1.000	Domainoid score	I3095
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6393
orthoMCL	1	0.900	-	-		OOG6_101017
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X128
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.830