Protein Alignment Irk2 and kcnj2b

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_017210355.1
• Gene: kcnj2b / 563744
• ZFINID: ZDB-GENE-091204-290
• Length: 440
• Species: Danio rerio
• Alignment Length: 363
• Identity: 162/363 - (44%)
• Similarity: 239/363 - (65%)
• Gaps: 16/363 - (4%)

  Fly    93 RRVRRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWL 157
            ::.:.|.|.|:|.|||...::..:..|:|.|::||.||.:|||.::.|.|||:||||.|.||:||
Zfish    43 QQTQNRFVNKDGRCNVQFINMSEKGQRYLADIFTTCVDIRWRWMMVLFFLSFLLSWLIFGLIFWL 107

  Fly   158 IIYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMC 222
            :.||.|||      :||.:.    |:|.:|.||:.||||:|||.|||||.|..:.:||.|:||:.
Zfish   108 VAYTSGDL------DNQVQI----CISNVDSFTAAFLFSVETQTTIGYGYRYVTEDCPIAVFMVV 162

  Fly   223 FQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGV 287
            ||||.|.:..||:.|.|.|||.:.|:|.:||:||::|.|..|||.|.||:|||::||||::.|.|
Zfish   163 FQSILGCIIDAFIIGAVMAKMAKPKKRNETLVFSQYATIAMRDGKLCLMWRVGNLRKSHLVEAHV 227

  Fly   288 RAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDKF 352
            ||||:::::|.|||.:.....::::|.|.....:|.:.|:.|.|:|||:||.|:::..::...:.
Zfish   228 RAQLLKSRTTAEGEFIPLDQLDIDVGFDTGIDRIFLVSPITIVHEIDEDSPFYDMSKQELESSEL 292

  Fly   353 EIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQV-DTPL 416
            ||||||||.||:|..:||.||||:.:||||||||:||:...|:  .|::||:.|..|.:| :||.
Zfish   293 EIVVILEGMVEATAMTTQCRSSYVTSEILWGHRFEPVLFEEKN--HYKVDYSHFENTYEVPNTPQ 355

  Fly   417 CSARELNE---IYKIQEGFRTPAETTFTMRQLSHNHSD 451
            ||||:|.|   |......|....|..|..::.:.:..|
Zfish   356 CSARDLAEKTYIMSNSNSFCYENEVAFMDKEETEDDDD 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	158/337 (47%)
kcnj2b	XP_017210355.1	IRK_N	2..49	CDD:312087	0/5 (0%)
		IRK	50..373	CDD:307239	157/334 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	195	1.000	Domainoid score	I3095
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6393
orthoMCL	1	0.900	-	-		OOG6_101017
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X128
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.930