Protein Alignment Irk2 and kcnj1a.1

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_957329.1
• Gene: kcnj1a.1 / 386933
• ZFINID: ZDB-GENE-031118-55
• Length: 370
• Species: Danio rerio
• Alignment Length: 336
• Identity: 128/336 - (38%)
• Similarity: 195/336 - (58%)
• Gaps: 9/336 - (2%)

  Fly    91 SMRRVRR-RAVFKNGDCNV-VQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFAL 153
            |.||.|: |.|.|:|.||: ....:.|.|..::.|.:||.|:.:||:.||.|..||.|||..|.|
Zfish    14 SERRGRKNRLVTKDGRCNIEFGNVMHRNRFAYVLDFWTTFVETRWRFILLYFVASFTLSWFIFGL 78

  Fly   154 IWWLIIYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAI 218
            ||:.:...:|||...:.|     .|..||..:::..|..||||:|||.|||:|....:.:||..:
Zfish    79 IWYWLARNNGDLLWQNPP-----PGHKPCAFSVNDMTYAFLFSLETQSTIGFGNIYVTDQCPGGV 138

  Fly   219 FMMCFQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHII 283
            .::..|:|.|:..:.|..|||..|::..|:||:|:.||:.||||.:.|||.|..||.::||:.:|
Zfish   139 ALIVIQTIIGLFINIFWCGIVMTKISLPKKRAKTITFSESAVICPKKGTLCLQIRVANLRKTLMI 203

  Fly   284 GAGVRAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDML 348
            |:.:..:|:||..| .||.:......::...|....:|||:.|:.:.|.||::||.:|:....|.
Zfish   204 GSQIYGKLLRTTVT-GGETVILDQVSIDFMVDAGKDNLFFVCPLTLYHIIDKSSPFFNMAVDTMH 267

  Fly   349 QDKFEIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVD 413
            |..||:||.|:|..|||..:.|.|:|||..||:||:.|.|::..:|: ..|.:|::.|.:...|.
Zfish   268 QQDFELVVFLDGMAESTSSACQVRTSYIPQEIMWGYDFLPIISRSKE-GRYRVDFSNFAKVVPVP 331

  Fly   414 TPLCSARELNE 424
            |..||....||
Zfish   332 TAHCSHCYHNE 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	123/326 (38%)
kcnj1a.1	NP_957329.1	IRK	24..166	CDD:366415	54/146 (37%)
		IRK_C	173..342	CDD:375232	63/170 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920