Protein Alignment Irk2 and LOC3290452

DIOPT Version :10

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_321865.3
• Gene: LOC3290452 / 3290452
• VectorBaseID: AGAMI1_000241
• Length: 452
• Species: Anopheles gambiae
• Alignment Length: 402
• Identity: 230/402 - (57%)
• Similarity: 296/402 - (73%)
• Gaps: 19/402 - (4%)

  Fly    27 EQATQPLKKAIEADPDSLDSVISNPQSYPITIVPNRPTSYYGLSQNGKPFPRQPSCRSRNFRPGS 91
            :::.:||.       |.....|..|.|   :..|..|..:..:..:|:        |..::|||
Mosquito    23 DRSPRPLN-------DKYSPSILTPDS---SSSPRSPFRFDSMRSSGR--------RPPHYRPG- 68

  Fly    92 MRRVRRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWW 156
            .::.|:|||||||.|||....:..:|:|||||::||:||.|||||||.|||.|:.||:.|..::|
Mosquito    69 YKKPRKRAVFKNGYCNVSATKVPHQRLRFLQDIFTTLVDAQWRWTLLVFALGFVSSWVLFGGLYW 133

  Fly   157 LIIYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMM 221
            ||.||||||:|.|||..|.::.|.||:|.|..||||||||:|||||||||.|....|||||:|:|
Mosquito   134 LISYTHGDLDENHLPPLQGDNNWTPCISNIYSFTSCFLFSLETQHTIGYGSRAMEEECPEAVFVM 198

  Fly   222 CFQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAG 286
            ..||::|||..||:||||||||||:|.|||||||||.|||.||||.|.||||:|||||||||||.
Mosquito   199 TLQSVHGVMVQAFLAGIVFAKMTRSKGRAQTLLFSKQAVISQRDGELCLMFRIGDMRKSHIIGAN 263

  Fly   287 VRAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDK 351
            |||||||.|.|.|.|||.||.||||:.:||..||:||:||.::.|:|||.||||..:|..:|.::
Mosquito   264 VRAQLIRAKVTGEREVMPQYRTELELTSDDCSSDVFFLWPQIVVHRIDEKSPLYGYSAEAVLLER 328

  Fly   352 FEIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPL 416
            |||||:||||||||||:||||:||:||||||||||:.|::||.|:::||||:::||||..::||.
Mosquito   329 FEIVVVLEGTVESTGQTTQARTSYVNTEILWGHRFEQVLVYNADIESYEIDFSKFNETVALETPR 393

  Fly   417 CSARELNEIYKI 428
            |||::|.|.:|:
Mosquito   394 CSAKQLKECFKL 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..246	CDD:460023	92/145 (63%)
		IRK_C	253..424	CDD:465439	114/170 (67%)
LOC3290452	XP_321865.3	IRK	77..222	CDD:460023	91/144 (63%)
		IRK_C	230..401	CDD:465439	114/170 (67%)