Protein Alignment Irk2 and Kcnj10

DIOPT Version :10

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_038946576.2
• Gene: Kcnj10 / 29718
• RGDID: 61822
• Length: 400
• Species: Rattus norvegicus
• Alignment Length: 351
• Identity: 137/351 - (39%)
• Similarity: 197/351 - (56%)
• Gaps: 20/351 - (5%)

  Fly    96 RRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIY 160
            |||.:.|:|..||..:|:..:|..:|:|::||.:|.|||:.||.|:.:|..:|..|.::|:|:..
  Rat    48 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWYLVAV 112

  Fly   161 THGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQS 225
            .||||.|...|.|.     .|||..:...|..||||:|:|.|||||.|..|.|||.||.::..|.
  Rat   113 AHGDLLELGPPANH-----TPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLLIAQL 172

  Fly   226 IYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQ 290
            :...:...|:.|...||:.|.|:||:|:.||:|||:...:|.|.||.||.:||||.:||..|..:
  Rat   173 VLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVAYHNGKLCLMIRVANMRKSLLIGCQVTGK 237

  Fly   291 LIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDKFEIV 355
            |::|..|||||.:......:....|.:....|.|.|:...|.:||.|||.:|.......| ||:|
  Rat   238 LLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSGEGD-FELV 301

  Fly   356 VILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQA---YEIDYARFNETTQVDTPLC 417
            :||.||||||..:.|.|:||:..|||||:.|.|.:    .|.|   |..|::.|::..:|.:| .
  Rat   302 LILSGTVESTSATCQVRTSYLPEEILWGYEFTPAI----SLSASGKYVADFSLFDQVVKVASP-G 361

  Fly   418 SARELNEIY------KIQEGFRTPAE 437
            ..|:....|      |::|..|..||
  Rat   362 GLRDSTVRYGDPEKLKLEESLREQAE 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..246	CDD:460023	56/145 (39%)
		IRK_C	253..424	CDD:465439	67/173 (39%)
Kcnj10	XP_038946576.2	None