Protein Alignment Irk2 and irk-3

DIOPT Version :10

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001368607.1
• Gene: irk-3 / 191696
• WormBaseID: WBGene00002151
• Length: 384
• Species: Caenorhabditis elegans
• Alignment Length: 328
• Identity: 110/328 - (33%)
• Similarity: 190/328 - (57%)
• Gaps: 25/328 - (7%)

  Fly    96 RRRAVFKNG-----DCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIW 155
            |.|.|.|:|     :..:.::..|..:.|:.::.:..:::..||...:.|.|.||:||..||:|:
 Worm    46 RARLVSKDGKTLLNNIQIPERFRQAYKWRYCRNWFHLIIECNWRTICILFLLGFIVSWTIFAVIY 110

  Fly   156 WLI--IYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAI 218
            ::|  :.|          ..::||    |::.:|...|.||||:|:|||||||:|..:..||.|.
 Worm   111 YVISRLKT----------VKKDES----CIANVDTLISAFLFSMESQHTIGYGLRYMTDLCPPAY 161

  Fly   219 FMMCFQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVI---CQRDGTLSLMFRVGDMR-K 279
            ..:|.|.:.||.....:||||.||:.|.|:|.|.:.||:.|||   .:.|...:||.|:.|:: |
 Worm   162 LTLCVQCVVGVFLQTILAGIVIAKILRPKKRRQEMRFSRMAVIGPLDEHDKRPTLMIRLADIQEK 226

  Fly   280 SHIIGAGVRAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNA 344
            ..:..:.||..:..:|....|:.......::.:|.|.....:..:||:::.|.|:|:||||.::.
 Worm   227 LFLAESHVRLYMACSKINSRGDRELIGVKDMNVGYDSGWDRVLLLWPIIVRHVINEDSPLYGMSR 291

  Fly   345 TDMLQDKFEIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNET 409
            .::::..||:::.:||.||:||.:.|||:|::..|||||::|.|:||.|:.|..||:.|:.|::|
 Worm   292 ENIVKADFELIMTVEGIVEATGMTFQARTSFLPDEILWGYKFKPMVLMNEKLSKYEVHYSFFDQT 356

  Fly   410 TQV 412
            .:|
 Worm   357 ERV 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..246	CDD:460023	49/152 (32%)
		IRK_C	253..424	CDD:465439	55/164 (34%)
irk-3	NP_001368607.1	IRK	50..189	CDD:460023	49/152 (32%)
		IRK_C	196..359	CDD:465439	54/162 (33%)