Protein Alignment Irk2 and irk-3

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001368607.1
• Gene: irk-3 / 191696
• WormBaseID: WBGene00002151
• Length: 384
• Species: Caenorhabditis elegans
• Alignment Length: 328
• Identity: 110/328 - (33%)
• Similarity: 190/328 - (57%)
• Gaps: 25/328 - (7%)

  Fly    96 RRRAVFKNG-----DCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIW 155
            |.|.|.|:|     :..:.::..|..:.|:.::.:..:::..||...:.|.|.||:||..||:|:
 Worm    46 RARLVSKDGKTLLNNIQIPERFRQAYKWRYCRNWFHLIIECNWRTICILFLLGFIVSWTIFAVIY 110

  Fly   156 WLI--IYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAI 218
            ::|  :.|          ..::||    |::.:|...|.||||:|:|||||||:|..:..||.|.
 Worm   111 YVISRLKT----------VKKDES----CIANVDTLISAFLFSMESQHTIGYGLRYMTDLCPPAY 161

  Fly   219 FMMCFQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVI---CQRDGTLSLMFRVGDMR-K 279
            ..:|.|.:.||.....:||||.||:.|.|:|.|.:.||:.|||   .:.|...:||.|:.|:: |
 Worm   162 LTLCVQCVVGVFLQTILAGIVIAKILRPKKRRQEMRFSRMAVIGPLDEHDKRPTLMIRLADIQEK 226

  Fly   280 SHIIGAGVRAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNA 344
            ..:..:.||..:..:|....|:.......::.:|.|.....:..:||:::.|.|:|:||||.::.
 Worm   227 LFLAESHVRLYMACSKINSRGDRELIGVKDMNVGYDSGWDRVLLLWPIIVRHVINEDSPLYGMSR 291

  Fly   345 TDMLQDKFEIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNET 409
            .::::..||:::.:||.||:||.:.|||:|::..|||||::|.|:||.|:.|..||:.|:.|::|
 Worm   292 ENIVKADFELIMTVEGIVEATGMTFQARTSFLPDEILWGYKFKPMVLMNEKLSKYEVHYSFFDQT 356

  Fly   410 TQV 412
            .:|
 Worm   357 ERV 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	108/324 (33%)
irk-3	NP_001368607.1	Ion_trans_2	50..189	CDD:419733	49/152 (32%)
		IRK_C	196..359	CDD:407551	54/162 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101017
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.780