Protein Alignment Irk2 and irk-1

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_509138.2
• Gene: irk-1 / 180944
• WormBaseID: WBGene00002149
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 424
• Identity: 166/424 - (39%)
• Similarity: 240/424 - (56%)
• Gaps: 44/424 - (10%)

  Fly    69 LSQNGKPF--PRQPSCRS----------RN----FRPGSMRRVRRRAVFKNGDCNVVQKHLQRRR 117
            |..||:|.  ||:.|...          ||    :|..:.:..:.|.|.|||.|||...::.::.
 Worm    29 LIANGRPSPPPRRTSLAESIRTLAFTARRNSSPLYRKSTKKLKKSRLVGKNGICNVYNTNVPKKD 93

  Fly   118 VRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIYTHGDLEEPHLPENQEESGWAPC 182
            .::|:|::|||:|.:|||.|:.||.:|:|||..|...::||...||||..| .|.|.     ..|
 Worm    94 RQYLRDIFTTMIDVKWRWMLMLFASAFVLSWSIFGTTYYLIALVHGDLSLP-TPVNH-----TAC 152

  Fly   183 VSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQSIYGVMSSAFMAGIVFAKMTRAK 247
            |..:|...|.|||::||.||||||.|..:.||..|..::|.|:|..::..:||.|||||||.|.|
 Worm   153 VMNLDSVYSSFLFAVETHHTIGYGHRYITTECYLAGAIVCLQAICALLLQSFMVGIVFAKMARPK 217

  Fly   248 QRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQLIRTKSTKEGEVMTQYFTELEI 312
            :||:|::||..||||.|||.|..:.||||||.:|::.|.||.|.|..:.|.|||:...:..|:::
 Worm   218 KRAETIIFSDKAVICLRDGQLCFLCRVGDMRNTHLVEAHVRLQFITDRETNEGEIEPLHQFEMKV 282

  Fly   313 GTDDSGSD-LFFIWPMVIEHKIDENSPLYNLNATDMLQDKFEIVVILEGTVESTGQSTQARSSYI 376
            |...:..| ||.:||..:.|.||..|||||.|...::..:|||:|:|||.|||||.:.||::||:
 Worm   283 GPSIADDDRLFLVWPTTLCHVIDSRSPLYNYNQQTLMSAQFEIIVLLEGIVESTGMTAQAKTSYL 347

  Fly   377 NTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPLCSARE-------LNEIY-------K 427
            .:|:||||||..:|.|.:...:|:|||..|:.|..|.||..|..|       |.:.|       |
 Worm   348 PSEVLWGHRFRKLVTYQRSNGSYQIDYDLFHSTYPVRTPAMSPAEFYSSKPNLKDYYCHDSHEHK 412

  Fly   428 IQEG-------FRTPAETTFTMRQLSHNHSDQAS 454
            :::.       ..:|:..::....|:|..|...|
 Worm   413 LEDNRSSDSTPLPSPSPYSYPSTPLNHFQSSSNS 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	150/355 (42%)
irk-1	NP_509138.2	IRK	76..405	CDD:279361	148/334 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I2606
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	1	1.000	-	-		FOG0000937
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101017
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.780