Protein Alignment Irk2 and Kcnj15

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_038943851.1
• Gene: Kcnj15 / 170847
• RGDID: 621662
• Length: 450
• Species: Rattus norvegicus
• Alignment Length: 460
• Identity: 151/460 - (32%)
• Similarity: 240/460 - (52%)
• Gaps: 40/460 - (8%)

  Fly     1 MRFNFSTH-SAAPTSTTIP------------TTTQANGGEQATQPLKKAIEADPDSLDSVISNPQ 52
            :|...||: |.||..|::|            .|.|..|.....:.....:|....||.|. ..|:
  Rat     9 LRKALSTYLSKAPRITSLPGLNFPPTQESALGTLQVRGQRVCQRGACSMVEMLQKSLSSK-GGPR 72

  Fly    53 SYPITIVPNRPTSYYGLSQNGKPFPRQPSCRSRNFRPG-SMRRVRRRAVFKNGDCNVVQKHLQRR 116
            |..:..:      :.|:|.       .|..:..|   | .::..|.|.:.|:|..||....:...
  Rat    73 SLRMEAI------HIGMSS-------APLVKHSN---GVGLKAHRPRVMSKSGHSNVRIDKVDGI 121

  Fly   117 RVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIYTHGDLEEPHLPENQEESGWAP 181
            .:.:|||::||::|.:||:.|..||.:|:::|..|.::::.|.:.|||||     ..:..|...|
  Rat   122 YLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVVYYAIAFIHGDLE-----LGESNSNHTP 181

  Fly   182 CVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQSIYGVMSSAFMAGIVFAKMTRA 246
            |:..:|..|..||||:|:|.|||||||:.:.|||.|||::..|.:...:...|:.|...||:.|.
  Rat   182 CIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARP 246

  Fly   247 KQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQLIRTKSTKEGEVMTQYFTELE 311
            |:||:|:.||..|||.:::|.|.|:.:|.:||||.:|...:..:|::|..|||||.:......::
  Rat   247 KKRAETIKFSHCAVISKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVK 311

  Fly   312 IGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDKFEIVVILEGTVESTGQSTQARSSYI 376
            ...|.|....|.|.||...|.:||.|||.:|...::.:.:||:||:|..|||||....|:|:|||
  Rat   312 FHVDSSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYI 376

  Fly   377 NTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPLCSAR-ELNEIYKIQEGFRTPAETTF 440
            ..||.||..|.|||..:|: ..|..|:::|.:..:  :|.|:.. ..:|..|::|.:|...:...
  Rat   377 PEEIYWGFEFVPVVSLSKN-GKYVADFSQFEQIRK--SPDCTFYCADSEKQKLEEQYRQEDQRER 438

  Fly   441 TMRQL 445
            .:|.|
  Rat   439 ELRSL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	124/334 (37%)
Kcnj15	XP_038943851.1	IRK	105..246	CDD:395797	53/145 (37%)
		IRK_C	253..424	CDD:407551	64/173 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930