Protein Alignment Irk2 and Kcnj10

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_006496740.3
• Gene: Kcnj10 / 16513
• MGIID: 1194504
• Length: 476
• Species: Mus musculus
• Alignment Length: 351
• Identity: 136/351 - (38%)
• Similarity: 196/351 - (55%)
• Gaps: 20/351 - (5%)

  Fly    96 RRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIY 160
            |||.:.|:|..||..:|:..:|..:|:|::||.:|.|||:.||.|:.:|..:|..|.::|:|:..
Mouse   124 RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWYLVAV 188

  Fly   161 THGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQS 225
            .||||.|...|.|.     .|||..:...|..||||:|:|.|||||.|..|.|||.||.::..|.
Mouse   189 AHGDLLELGPPANH-----TPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLLIAQL 248

  Fly   226 IYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQ 290
            :...:...|:.|...||:.|.|:||:|:.||:|||:...:|...||.||.:||||.:||..|..:
Mouse   249 VLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGK 313

  Fly   291 LIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDKFEIV 355
            |::|..|||||.:......:....|.:....|.|.|:...|.:||.|||.:|.......| ||:|
Mouse   314 LLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSGEGD-FELV 377

  Fly   356 VILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQA---YEIDYARFNETTQVDTPLC 417
            :||.||||||..:.|.|:||:..|||||:.|.|.:    .|.|   |..|::.|::..:|.:| .
Mouse   378 LILSGTVESTSATCQVRTSYLPEEILWGYEFTPAI----SLSASGKYIADFSLFDQVVKVASP-S 437

  Fly   418 SARELNEIY------KIQEGFRTPAE 437
            ..|:....|      |::|..|..||
Mouse   438 GLRDSTVRYGDPEKLKLEESLREQAE 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	130/342 (38%)
Kcnj10	XP_006496740.3	IRK	129..269	CDD:366415	56/144 (39%)
		IRK_C	276..451	CDD:375232	67/180 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930