Protein Alignment Irk2 and LOC1281897

DIOPT Version :10

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_061507888.1
• Gene: LOC1281897 / 1281897
• VectorBaseID: AGAMI1_000343
• Length: 556
• Species: Anopheles gambiae
• Alignment Length: 463
• Identity: 229/463 - (49%)
• Similarity: 287/463 - (61%)
• Gaps: 73/463 - (15%)

  Fly    27 EQATQPLKKAIE-ADPDS-------LDS--------VISNPQSYP-----------ITIVPNR-- 62
            |.|.|..:.|.: ||||:       ||.        :|..|.:.|           :|:.|..
Mosquito     6 EDARQTDRSAQDGADPDAAGCWTKLLDDTSATHKQPIIVGPAARPDPGSDIVKELLVTVDPETGK 70

  Fly    63 --PTSYYGLSQNGK--------------PFPRQ-------------PSCRSRNFRPGSMRRVRRR 98
              ..:..|.:.||:              .|.||             |..|.|..|..| ||:|:|
Mosquito    71 TGQQAIDGAANNGEQRVAGGRRRESILGTFHRQLRMSLKAVSETPGPLTRYRQTRYSS-RRIRKR 134

  Fly    99 AVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIYTHG 163
            .:||.|||||:|.::.:||.|:|||::||:||.||||||..||.|||||||.|..||:||..:||
Mosquito   135 VIFKQGDCNVIQGNVAKRRRRYLQDIFTTLVDIQWRWTLFVFACSFILSWLGFGAIWYLIALSHG 199

  Fly   164 DL----EEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQ 224
            |:    :|.|          .|||:.|.||||.||||:|||||||||.|..:.||||.||::..|
Mosquito   200 DIQAVGDESH----------KPCVTYIYGFTSAFLFSLETQHTIGYGNRYITEECPEGIFILALQ 254

  Fly   225 SIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRA 289
            ||.||...|||.||||||::|.|:|||||||||:||||.|||...|:||||||||||||.|.|.|
Mosquito   255 SITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSKNAVICHRDGMPCLLFRVGDMRKSHIIEAHVTA 319

  Fly   290 QLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDKFEI 354
            |:||.|.||||||:..|...:|:..|.....|.||||.::.||||.:||||.|:|.|||:::|||
Mosquito   320 QIIRRKVTKEGEVLPFYQQNMEVSCDGGDDRLMFIWPTIVVHKIDRDSPLYGLSAQDMLKERFEI 384

  Fly   355 VVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPLCSA 419
            ||:|||.|||||.:|||||||:.:||||||||:.||.:.::...||:||..||.|.:||||||||
Mosquito   385 VVMLEGVVESTGMTTQARSSYLPSEILWGHRFESVVTFKRETGEYEVDYTTFNNTYEVDTPLCSA 449

  Fly   420 RELNEIYK 427
            |:|.|:.|
Mosquito   450 RQLREVKK 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..246	CDD:460023	85/149 (57%)
		IRK_C	253..424	CDD:465439	106/170 (62%)
LOC1281897	XP_061507888.1	None