Protein Alignment Irk2 and kcnj3

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_002936698.1
• Gene: kcnj3 / 100380084
• XenbaseID: XB-GENE-1004371
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 356
• Identity: 153/356 - (42%)
• Similarity: 222/356 - (62%)
• Gaps: 8/356 - (2%)

  Fly    81 SCRSRNFRPGSMRRVRRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFI 145
            |.....|...:.:|.|:|.|.|||.|||...:|.....|:|.|::||:||.:|||.|..|.|::.
 Frog    18 SSSGSGFNQAAPKRKRQRFVEKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYT 82

  Fly   146 LSWLFFALIWWLIIYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTT 210
            ::|||.|.:||:|.|..|||.:.|      :..:.|||:.:..|.|.|||.|||:.|||||.|..
 Frog    83 VAWLFMASMWWVIAYMRGDLNKAH------DENYTPCVANVYNFPSAFLFFIETEATIGYGFRYI 141

  Fly   211 SPECPEAIFMMCFQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVG 275
            :.:|||.|.:..||||.|.:..||:.|.:|.||::.|:||:||:||:||||..|||.|:||||||
 Frog   142 TDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVG 206

  Fly   276 DMRKSHIIGAGVRAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLY 340
            ::|.||::.|.:|.:|::::.|.|||.:.....||::|.......||.:.|:.|.|.||..||.|
 Frog   207 NLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDTKSPFY 271

  Fly   341 NLNATDMLQDKFEIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYAR 405
            .|:...|..::|||||||||.||:||.:.|||:||...|:||||||.||:...:..  :::||::
 Frog   272 ELSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGF--FKVDYSQ 334

  Fly   406 FNETTQVDTPLCSARELNEIYKIQEGFRTPA 436
            |:.|.:|.|...|.:|..::..:......||
 Frog   335 FHATFEVPTAPYSVKEQEDMLLMSSPLIAPA 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	146/333 (44%)
kcnj3	XP_002936698.1	IRK	37..354	CDD:279361	146/324 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	201	1.000	Domainoid score	I2943
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	363	1.000	Inparanoid score	I2130
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9384
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.080