Protein Alignment Irk2 and kcnj3a

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_002663356.2
• Gene: kcnj3a / 100330491
• ZFINID: ZDB-GENE-100922-16
• Length: 490
• Species: Danio rerio
• Alignment Length: 344
• Identity: 152/344 - (44%)
• Similarity: 219/344 - (63%)
• Gaps: 8/344 - (2%)

  Fly    93 RRVRRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWL 157
            ||.|:|.|.|||.|||...:|.....|:|.|::||:||.:|||.|..|.|::.::|||.|.:||:
Zfish    27 RRKRQRFVDKNGRCNVQHGNLGGETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMAFMWWV 91

  Fly   158 IIYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMC 222
            |.|..|||...|      :..:.|||:.:..|.|.|||.|||:.|||||.|..:.:|||.|.:..
Zfish    92 IAYIRGDLNRTH------DEKYTPCVANVYNFPSAFLFFIETEATIGYGHRYITDKCPEGIILFL 150

  Fly   223 FQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGV 287
            ||||.|.:..||:.|.:|.||::.|:||:||:||::|.|..|||.|:||||||::|.||::.|.:
Zfish   151 FQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSENAAISMRDGKLTLMFRVGNLRNSHMVSAQI 215

  Fly   288 RAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDKF 352
            |.:|::::.|.|||.:.....||::|.......||.:.|:.|.|.||..||.|.|:...|..::|
Zfish   216 RCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDTKSPFYELSQHSMQTEQF 280

  Fly   353 EIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPLC 417
            ||||||||.||:||.:.|||:||...|:||||||.||:...:..  :::||::|:.|.:|.||..
Zfish   281 EIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGF--FKVDYSQFHATFEVPTPPY 343

  Fly   418 SARELNEIYKIQEGFRTPA 436
            ||:|.:|...:......|:
Zfish   344 SAKEQDEALLMSSPLMAPS 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	147/333 (44%)
kcnj3a	XP_002663356.2	IRK	34..350	CDD:279361	146/323 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580683
Domainoid	1	1.000	195	1.000	Domainoid score	I3095
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	366	1.000	Inparanoid score	I2116
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6353
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	9.010