DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Irk2 and LOC100329607

DIOPT Version :9

Sequence 1:	NP_001287485.1	Gene:	Irk2 / 42770	FlyBaseID:	FBgn0039081	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_009297229.1	Gene:	LOC100329607 / 100329607	-ID:	-	Length:	413	Species:	Danio rerio

Alignment Length:	372	Identity:	132/372 - (35%)
Similarity:	192/372 - (51%)	Gaps:	35/372 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 PTSYYGLSQNGKPFPRQPSCRSRN----FRP-----GSMRRV--RRRAVFKNGDCNVVQKHLQRR 116
            |..::|      |.| |..|.|:.    .:|     |....|  :||.:.|:|..||..:|:...
Zfish     6 PPPHHG------PAP-QKVCHSQTQTDLLKPLLGGAGHSSHVARKRRILTKDGRSNVRIEHVSGL 63

  Fly   117 RVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIYTHGDLEEPHLPENQEESGWAP 181
            ...:|:|.:||:||.|||:.|:.|:.:|:.:|..|.|:|:|:...||||.|...|.|.     :.
Zfish    64 SALYLRDPWTTVVDMQWRYKLVLFSATFVGTWFTFGLLWYLLALVHGDLLEFDPPANH-----SV 123

  Fly   182 CVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQSIYGVMSSAFMAGIVFAKMTRA 246
            ||..:...|..||||:|||.|||||.|..:.|||.||.::..|.:.......|:.|...||:.|.
Zfish   124 CVMQMQTLTGAFLFSLETQTTIGYGYRCITEECPSAIVLLIIQLLITTAMEIFITGTFLAKVARP 188

  Fly   247 KQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQLIRTKSTKEGEVMTQYFTELE 311
            |:|.:|:.||:||||...||..|||.||.:||||.::|..|..:|::....|.||.:......:.
Zfish   189 KKRGETIRFSQHAVIANHDGRPSLMIRVANMRKSLLLGCQVTGKLLQPCVPKAGETVRLDQKNVS 253

  Fly   312 IGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNA--------TDMLQDKFEIVVILEGTVESTGQS 368
            ...|.:....|.|.|:...|.||:.||   |.|        ||..|..||::|::..|||.|..:
Zfish   254 FSVDTASESPFLILPLTFYHIIDDESP---LRAWADKGGGWTDPGQTDFELLVMMSSTVEPTSAT 315

  Fly   369 TQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTP 415
            .|.|:||:..|||||:.|.|:|..: .:..|..|.|.|::..:...|
Zfish   316 CQVRTSYLPDEILWGYEFPPIVSLS-PMGKYVADLAYFDKVVKTKAP 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	120/324 (37%)
LOC100329607	XP_009297229.1	Ion_trans_2	47..393	CDD:304432	120/324 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020