Protein Alignment Irk2 and kcnj13

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_001096437.1
• Gene: kcnj13 / 100125048
• XenbaseID: XB-GENE-983214
• Length: 374
• Species: Xenopus tropicalis
• Alignment Length: 369
• Identity: 118/369 - (31%)
• Similarity: 189/369 - (51%)
• Gaps: 31/369 - (8%)

  Fly    78 RQPSCRSRNFRPGSMRRVRRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFAL 142
            |.|.|.       .:.....|.|.|:|...|....:|.:.:.:|:|::..::|.:|||.:|||:.
 Frog    16 RSPKCT-------LLSPCTHRLVTKDGHSMVKAGRMQGQGLTYLRDIWGLLLDMRWRWMMLAFSA 73

  Fly   143 SFILSWLFFALIWWLIIYTHGDLEEPH--LPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGY 205
            ||:..||.||:.|:|:...:|||...|  .|||.     ..||..|..||:.|.||:|||.||||
 Frog    74 SFLAHWLLFAVFWYLLAEMNGDLAVDHDAPPENH-----TICVKYITSFTAAFSFSLETQLTIGY 133

  Fly   206 GVRTTSPECPEAIFMMCFQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSL 270
            |....|.:||.||.::..|.:.|:|..||:.|:..||:.|.|.|..::.||:.||:...:|...|
 Frog   134 GTMFPSGDCPSAIALLAVQMLLGLMLEAFITGVFVAKIARPKNRTPSIRFSRLAVVGSPEGKPCL 198

  Fly   271 MFRVGDMRKSHIIGAGVRAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDL-FFIWPMVIEHKID 334
            ||:|.:.|.|.:....|...|.:.:.  :|::. |...|..:.:..||::. ||.:|:...|.:.
 Frog   199 MFQVANTRSSPLTMVKVSGILYQERG--DGQIQ-QANVEFSLDSQASGAECPFFTFPLTYSHSLC 260

  Fly   335 ENSPLYNLNATDMLQD--KFEIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVL------ 391
            ..|||..|...::|..  ..|:||.|..|.||:|:..|.|:||:.:|||.||||.|.:.
 Frog   261 SGSPLSVLLQRELLSSAGHLELVVCLSATQESSGEICQCRTSYLPSEILQGHRFAPCLTRRLEGG 325

  Fly   392 YNKDLQAY-----EIDYARFNETTQVDTPLCSARELNEIYKIQE 430
            |...::::     |:......:..:.|..:|:..:..:.::|.|
 Frog   326 YRICMESFGRPLPELPQPSHRQLYRTDLEVCANGQRGDTFQICE 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	114/347 (33%)
kcnj13	NP_001096437.1	Ion_trans_2	31..174	CDD:389812	58/147 (39%)
		IRK_C	181..348	CDD:375232	49/169 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D956263at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010