Protein Alignment Irk2 and kcnj19b

DIOPT Version :9

• Sequence 1: NP_001287485.1
• Gene: Irk2 / 42770
• FlyBaseID: FBgn0039081
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: XP_001340328.2
• Gene: kcnj19b / 100000044
• ZFINID: ZDB-GENE-121214-60
• Length: 505
• Species: Danio rerio
• Alignment Length: 332
• Identity: 148/332 - (44%)
• Similarity: 218/332 - (65%)
• Gaps: 8/332 - (2%)

  Fly    93 RRVRRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWL 157
            :|.|:|.|.|||.|||...:|.....|::.|::||:||.:|||.||.|.|::.::||..|.:||:
Zfish    28 KRKRQRFVEKNGRCNVQHGNLGGETSRYISDLFTTLVDLKWRWNLLIFLLTYTVAWLIMASMWWI 92

  Fly   158 IIYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMC 222
            |.|..|||...|      :..:.|||:.:..|.|.|||.|||:.|||||.|..:.:|||.|.:..
Zfish    93 IAYIRGDLGHGH------DDSYTPCVANVYNFPSAFLFFIETEATIGYGYRYITEKCPEGIILFL 151

  Fly   223 FQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGV 287
            |||:.|.:..||:.|.:|.||::.|:||:||:||:.|||.||||.|.||||||::|.||::.|.:
Zfish   152 FQSLLGSIVDAFLIGCMFIKMSQPKKRAETLMFSQDAVISQRDGKLCLMFRVGNLRNSHMVSAQI 216

  Fly   288 RAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQDKF 352
            |.:||:::.|.|||.:.....||::|.......||.:.|:.|.|:|:.|||.::|:...::.::|
Zfish   217 RCKLIKSRQTPEGEFLPLDQRELDVGFGTGADQLFLVSPLTICHEINSNSPFFDLSQRSLMNEQF 281

  Fly   353 EIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPLC 417
            ||||||||.||:||.:.|||:||...|:||||||.||:...:..  :.:||::|:.|.:|.||..
Zfish   282 EIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFLPVMSLEEGF--FRVDYSQFHNTFEVPTPPY 344

  Fly   418 SARELNE 424
            |.:|.:|
Zfish   345 SVKEQDE 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk2	NP_001287485.1	IRK	100..434	CDD:279361	145/325 (45%)
kcnj19b	XP_001340328.2	IRK	35..352	CDD:279361	145/325 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580681
Domainoid	1	1.000	195	1.000	Domainoid score	I3095
eggNOG	1	0.900	-	-		E1_KOG3827
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	366	1.000	Inparanoid score	I2116
OMA	1	1.010	-	-		QHG59160
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6353
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X128
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.910