DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir94g and Ir67c

DIOPT Version :9

Sequence 1:	NP_651147.2	Gene:	Ir94g / 42768	FlyBaseID:	FBgn0039079	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_729609.1	Gene:	Ir67c / 317838	FlyBaseID:	FBgn0052058	Length:	573	Species:	Drosophila melanogaster

Alignment Length:	574	Identity:	115/574 - (20%)
Similarity:	218/574 - (37%)	Gaps:	118/574 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GQELTSIFFYAPAKEKCHLEDTISSATWGLPLVIWRTDRTVILNGFIGEGLLVLACLPGFHWRAL 83
            |||::::|..:.|                        |:..||..|.... |::||.........
  Fly    51 GQEVSNLFVNSTA------------------------DKMKILGRFSSHS-LIIACFKDSTRNRT 90

  Fly    84 LGSLARSLKYLRQARILIELMQDRDEFLVSEVLQFCLSQDMINVNAIFDDFPETENLSSFEAYPS 148
            |..:...|..|:...||..:..:.|.:     .|..|....|:|.|:  :| ...:|.:::.||.
  Fly    91 LNGVKELLWGLQYLPILFVVDSNMDFY-----FQQALRHGFIHVLAL--NF-MNGSLYTYKPYPK 147

  Fly   149 FEVVNQTFTPDTQVSDLYP----NKMLNLRGGVIRTMPDYSEPNTILYQDKEGNKEILGYLWDLL 209
            .||        .|:.|:..    .|:.||:|..:||..:...|....|:::.|.....||::.::
  Fly   148 VEV--------HQIKDMQKFYKLTKLRNLQGQAVRTTVETMTPRCFRYRNRHGQLVYAGYMYRMV 204

  Fly   210 EAYAHKHNAQLQVVNKYADDRPLNFIELLDAAQSGIIDVGASIQPMSMGSLS-----RMHEMSYP 269
            :.:...:|...:.|....|..|  :.|.|.|.::|.||    :.|..:.:|.     |.| :.|.
  Fly   205 KEFISTYNGTEEHVFGNVDTVP--YKEGLAALKNGEID----MMPRIIHALEWYYFYRSH-ILYN 262

  Fly   270 VN---QASWCTMLPVERQLHVSE------LLTRVIPYPTLALLLLLWI-------------FYEV 312
            :.   ...|...||  :.|:..:      .:|.::.: ..|.:::.||             |.:|
  Fly   263 IKTYIMVPWAEPLP--KSLYFIQPFRGTVWITIMVSF-VYASIVIWWIRYRQQGNSSLTQSFMDV 324

  Fly   313 LR--------GRWR----RHSRLQSIGWLVLATLVSSNYVGKLLNLFTDPPSLPPVNSLAALMES 365
            |:        ..|.    .|..:..|...|...::::.|..:|.:..|.......:|:...|...
  Fly   325 LQLLFQLPLSKIWHFNMGTHQVVSFIVLFVFGFMLTNLYTAQLSSYLTTGLFKSQINTFDDLFRE 389

  Fly   366 PVRIISIRSEYSAIEFTQRTKYSAAFHLALHASILIGL-------RNAFNTSYGYTITSEKWKIY 423
            . |.:.:.| :.|......|| .........:.|||..       |.:.||||.|....::....
  Fly   390 K-RTLLVES-FDAEVLHNMTK-EKIIQKEFESIILITSIEEVFKHRKSLNTSYAYEAYEDRIAFE 451

  Fly   424 EEQQKRSSKPVFRYSKDLCFYEMIPFGLVIPENSPHRAPLHSYTLLLRQAGLHDFWV---NRGFS 485
            ..||:....|:|:..|::  |:..|..:.:....|:....::|...:.::|:   |:   ...|.
  Fly   452 LSQQRYLRVPIFKILKEV--YDQRPVFVALRHGLPYVELFNNYLRRIFESGI---WIKLQEDSFL 511

  Fly   486 YMVKAGKINFTAVGERYEAKTLTITDLRNVFIIYVSVLLISLILFTCELFVS-W 538
            ..:.:|:|:|    .:.:::.:.|.|....|..|: :|.:...:.|..||:. |
  Fly   512 EGIASGEISF----RKSKSREIKIFDKDFYFFAYI-LLGMGWCVSTIALFLELW 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir94g	NP_651147.2	None
Ir67c	NP_729609.1	Lig_chan	288..500	CDD:278489	39/217 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010