DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4374 and zld

DIOPT Version :10

Sequence 1:NP_651146.2 Gene:CG4374 / 42767 FlyBaseID:FBgn0039078 Length:772 Species:Drosophila melanogaster
Sequence 2:NP_608356.1 Gene:zld / 32994 FlyBaseID:FBgn0259789 Length:1596 Species:Drosophila melanogaster


Alignment Length:975 Identity:195/975 - (20%)
Similarity:290/975 - (29%) Gaps:375/975 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 PDMGIGIGVGVG-VGVESLGVSLHQ--------QQQQHHQNHQQPPHSHNGHNNNNNNNNNHVQV 91
            ||.|.|.|:||| :|    |.::.|        ||||||.||.|  ...||:.|...|...::|.
  Fly   654 PDYGGGGGLGVGAMG----GAAMSQYSASPSPTQQQQHHLNHHQ--QQANGYANGTANGYGYMQQ 712

  Fly    92 VHQPITSQSQQQSLCGGTRTNSNNM---------------IHDGG--GGGAGGGGGVVVPVGNR- 138
            ..|..|:.|.|.:    :..||||.               .|...  .|...|..|...|..|. 
  Fly   713 QVQSTTNASPQHA----SNNNSNNQQQQQQQQQHHQQQMPQHHNSVLNGHPNGLAGPSAPHNNNT 773

  Fly   139 ------------NGTSNGGDPT----------------------------LQGYEFWH------- 156
                        |.|:....||                            ::.....|       
  Fly   774 TQMPSSQMRGLLNETTTTPPPTTTTRAPQITTTATTTTTAATTVAIKSEQMEDSNHTHTHTHTHP 838

  Fly   157 -----QDKDNSRLDSSSIF------------EDLDRYCWQQQ-----------------PVTTSA 187
                 ||:.:|...|||:.            |..|.:..|.|                 |.|.|:
  Fly   839 NHSHSQDRSHSSSSSSSMATEEAEEQELRDQEQADDHLHQHQQASQQYLLSARHYHSSTPNTLSS 903

  Fly   188 SNGG----------------------SASTNQPSPTSPQGHL----------------------- 207
            ||..                      |.:|..|.|..|.|.|                       
  Fly   904 SNTNPSTPSSNSPHTIYRQEQQGTDFSRTTPPPQPLPPMGMLPPMAMDYNMLALDMPMPMPTLMH 968

  Fly   208 --------------------------------------------------QQQQQ----HQQHQQ 218
                                                              |.|:|    |||.::
  Fly   969 SNMLQCSSTSTTPLATTITTSMPDTMQPPQQQLVHHYQAVLHPLHQQLGEQHQRQEADHHQQQRE 1033

  Fly   219 LQQQQQQQQQQQ--------PNANSSSAASSGAGSSSDTISSLDTTDGQIYTLTVLNGGEPWLKR 275
            |.|..|||||||        |:::||..:||...:....::::....     |..|....|.:  
  Fly  1034 LHQLDQQQQQQQALILADSLPHSSSSPTSSSPPPTMPMPLTTITAPQ-----LLPLQPPPPHI-- 1091

  Fly   276 SESEQLPTSLDLDSLLGSFPGYIKSEYPYDDS-GFSTDGKDVIGN------GTDGLSSISQPQNQ 333
            :.:..:|.::.: .::...|...:...|.|.: .:.|    :||:      ||.|....:|....
  Fly  1092 TSTMPMPPTMHM-PIMPPPPQCYQQLQPLDPTMSYHT----IIGSGPEAHTGTAGGGYSNQITTS 1151

  Fly   334 GQQAQQTLPSLVTAISLAGGNDLGQQLAQFQNNNNDWHMADHNTETEQSTAES------LLRSAL 392
            ..|..|.:|:.:.|....                    ::.::...::|..|.      .|.:||
  Fly  1152 DGQILQLMPTSLFAPYAP--------------------LSPYSVAAQRSPQEGDLPPVHTLTTAL 1196

  Fly   393 QGKGYAKGLHMQNGL------TMPVVKDEDMRRLLFADEAAALGFADSTLSAAQMFDEAQGIHLS 451
            ..       |.|.|.      |:.|:.......:..:....||....:||.......|.:...:.
  Fly  1197 HA-------HQQGGQQEAQTPTLTVLSTPYSPTVSSSRATPALEMDMATLMQHHQDYEMEQYQMQ 1254

  Fly   452 SQQQQQQQQQQQQA-HNGNANILVDDMFLSLENAFSDDFEKIKRIANEVQQFCSAGSSGTPTPGD 515
            .||..|.||.|||. |.....||.|    ..:........|.:|           |.:.||:...
  Fly  1255 HQQLDQMQQHQQQLDHQQQQQILAD----QTQTMAQQPLAKKRR-----------GGNATPSTTK 1304

  Fly   516 YVPSSDVLMQISPSPAVTSAGQLQPPQPLKPEVSTSTSPTSAVVASAASNHVRSGGGVVKPKKAY 580
            ...:|.|                           .||||.|..:.|          |.:|..:..
  Fly  1305 RRRNSSV---------------------------GSTSPHSTTLPS----------GRIKCLECD 1332

  Fly   581 KRSSSNNNNPNVANNNQS--SGGNPLIAGSGSGSSSSSGSASSSSNSPPANSGGSSSSSSGSTQR 643
            |..:   .|..:..:|:|  ||..|.       .....|....|.:....:.|         ..|
  Fly  1333 KEFT---KNCYLTQHNKSFHSGEYPF-------RCQKCGKRFQSEDVYTTHLG---------RHR 1378

  Fly   644 KERSLHYCSICAKGFKDKYSVNVHIRT-HTGEKPFACSLCGKSFRQKAHLAKHYQTHMTQKNNGN 707
            .:...|.|.:|.|.|..|..:..|:.. |||.|...|.:|.|.|.:|.||.||.:||    |...
  Fly  1379 TQDKPHKCELCPKQFHHKTDLRRHVEAIHTGLKQHMCDICEKGFCRKDHLRKHLETH----NRPR 1439

  Fly   708 IIKGGSGKHQRSSGSSAGSARASLNQRQQQLGGGVVPPSLPVMISNPNT-------PPGGVLPPA 765
            ::    ||  :|:.::|.:|.|:.......|||.....|:....:...|       |..||..|:
  Fly  1440 VV----GK--KSAAAAAAAAAAAAVTATAGLGGAPAAGSIKAAFARSLTVTAVSSEPGAGVAIPS 1498

  Fly   766  765
              Fly  1499  1498

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4374NP_651146.2 zf-C2H2_4 649..671 CDD:464025 7/22 (32%)
C2H2 Zn finger 651..671 CDD:275370 6/20 (30%)
zf-H2C2_2 667..688 CDD:463886 9/21 (43%)
C2H2 Zn finger 679..699 CDD:275370 9/19 (47%)
zldNP_608356.1 zf-C2H2_jaz 552..577 CDD:432381
SUF4-like 1325..>1366 CDD:411020 9/50 (18%)
C2H2 Zn finger 1328..1349 CDD:411020 4/23 (17%)
C2H2 Zn finger 1328..1349 CDD:275368 4/23 (17%)
C2H2 Zn finger 1357..1377 CDD:275368 3/28 (11%)
C2H2 Zn finger 1386..1407 CDD:275368 6/20 (30%)
zf-C2H2 1413..1435 CDD:395048 9/21 (43%)
C2H2 Zn finger 1415..1435 CDD:275368 9/19 (47%)
Blue background indicates that the domain is not in the aligned region.

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