DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4408 and Agtpbp1

DIOPT Version :9

Sequence 1:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001364026.1	Gene:	Agtpbp1 / 67269	MGIID:	2159437	Length:	1218	Species:	Mus musculus

Alignment Length:	330	Identity:	67/330 - (20%)
Similarity:	106/330 - (32%)	Gaps:	104/330 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 LEQASDSCSFMGHARQP-----GQK------LTIMVTGAKVADFDDLVHSYNVTHRVLNYNFQAL 156
            :...:|.|.:..|..:.     |||      :|..|......|.....:.|..|:..|..:.|.|
Mouse   790 IRMGTDICYYKNHFSRSSVAAGGQKGKSYYTITFTVNFPHKDDVCYFAYHYPYTYSTLQMHLQKL 854

  Fly   157 IDANYLEVAPEDTKPEEFDWKR----------YHPLESINAWLKKLAETHPEVLLVELGVSAQGR 211
            ..|:         .|::..:::          ..||.:|.|.        ||....|.....:.|
Mouse   855 ESAH---------NPQQIYFRKDVLCETLSGNICPLVTITAM--------PESNYYEHICQFRTR 902

  Fly   212 PILGVQIAFDNENRTTVFVESGIHARE----WIAPATATYIIDQLVNSKDSAVQALARSQRWYIF 272
            |.              :|:.:.:|..|    |:...|..|::     |.....|:|..|..:.|.
Mouse   903 PY--------------IFLSARVHPGETNASWVMKGTLEYLM-----SNSPTAQSLRESYIFKIV 948

  Fly   273 PTVNPDGYQYTFKGDRMWRKNRALFGIC--RGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASE 335
            |.:||||   ...|:..          |  .|.||||    .|........|..|...|
Mouse   949 PMLNPDG---VINGNHR----------CSLSGEDLNR----QWQSPNPELHPTIYHAKG------ 990

  Fly   336 VETQRMIEFIRHRVESERI-RTFISLHSYS-QMIMFPYGHS-AERVDNYHD-------LTDIGKL 390
                    .:::....:|: ..:...|.:| :..:|.||.| .|.|.:.||       :.|:|..
Mouse   991 --------LLQYLAAVKRLPLVYCDYHGHSRKKNVFMYGCSIKETVWHTHDNSASCDIVEDMGYR 1047

  Fly   391 AANKI 395
            ...||
Mouse  1048 TLPKI 1052

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416	14/66 (21%)
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	51/233 (22%)
Agtpbp1	NP_001364026.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	476..512
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	590..617
		Pepdidase_M14_N	704..838	CDD:407865	9/47 (19%)
		M14_Nna1	861..1131	CDD:349477	51/250 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1193..1218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900