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Protein Alignment CG4408 and CPA4

DIOPT Version :9

Sequence 1:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_057436.2	Gene:	CPA4 / 51200	HGNCID:	15740	Length:	421	Species:	Homo sapiens

Alignment Length:	451	Identity:	129/451 - (28%)
Similarity:	224/451 - (49%)	Gaps:	56/451 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 WLLL---LLVSSVCVIQESKASSFCTKADQCALDEEIKTAADSVQARYDHTRIYQVELASEEHV- 97
            |:|.   |:.||:|                             .|.::...::.::.:.:.:.:
Human     3 WILFIGALIGSSIC-----------------------------GQEKFFGDQVLRINVRNGDEIS 38

  Fly    98 RLFQALEQASDSCSFMGHARQPGQKLTIMVTGAKVADFDDLVHSYNVTHRVLNYNFQALIDANYL 162
            :|.|.:...:...:|........:.:.::|....:..|...:.|..:.:.|...:.|||:|....
Human    39 KLSQLVNSNNLKLNFWKSPSSFNRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDD 103

  Fly   163 EV---APEDTKPEEFDWKRYHPLESINAWLKKLAETHPEVL-LVELGVSAQGRPILGVQIAF-DN 222
            |:   ..::.....|::..||.||:|...:..:|...|::. .|::|.|.:.||:..::.:. ..
Human   104 EMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG 168

  Fly   223 ENRTTVFVESGIHAREWIAPATATYIIDQLVN--SKDSAVQALARSQRWYIFPTVNPDGYQYTFK 285
            ..|..|::.:|||:||||:.|||.:...::|:  .:|.|:.::......::.|..|||||.||..
Human   169 VRRPAVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 233

  Fly   286 GDRMWRKNRAL--FGICRGVDLNRNFPFHWNVT----GASGDPCRYDYSGPSAASEVETQRMIEF 344
            .:|:|||.|:.  ...|.|.|.|||    ||.:    |||.:||...|.||.|.||||.:.:::|
Human   234 QNRLWRKTRSRNPGSSCIGADPNRN----WNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDF 294

  Fly   345 IRHRVESERIRTFISLHSYSQMIMFPYGHSAERVDNYHDLTDIGKLAANKIKDVSGRIYKSGSIY 409
            |:   :....:.||.||||||::|:|||:|.::..:..:|..:.:|||..:..|||..|:.|...
Human   295 IQ---KHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTC 356

  Fly   410 ETIYPSSGGSKDWAHGQLKIPITFSYELRGPADSEDLFILSAKEIEPTAAEAFASIQTIVQ 470
            .|:||:||.|.|||:.. .|...|::|||......  |:|.|.:|.|||.|.:..::||::
Human   357 TTVYPASGSSIDWAYDN-GIKFAFTFELRDTGTYG--FLLPANQIIPTAEETWLGLKTIME 414

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.