DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4408 and Cpa5

DIOPT Version :9

Sequence 1:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001002808.2	Gene:	Cpa5 / 408212	RGDID:	1303098	Length:	436	Species:	Rattus norvegicus

Alignment Length:	409	Identity:	128/409 - (31%)
Similarity:	211/409 - (51%)	Gaps:	15/409 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 QARYDHTRIYQVELASEEHVRLFQALE-QASDSCSFMGHARQPGQKLTIMVTGAKVADFDDLVHS 141
            |..:...::.:|...:|:.:.|.:.|| |......|.....:|...:.:.|..:::......:.|
  Rat    34 QVNFTGDQVLRVLAKNEKQLSLLRDLEIQKPQKVDFWRGPARPSLPVDMRVPFSELPSVKAYLKS 98

  Fly   142 YNVTHRVLNYNFQALIDANYLEVAPE---DTKPEEFDWKRYHPLESINAWLKKLAETHPE-VLLV 202
            :.:.:.|:..:.|.|:|.....:|..   :.....|.:..||.||.|..|:......|.. |..:
  Rat    99 HGLAYSVMIKDIQVLLDEERDAMARSRRLERSTNGFSYSSYHTLEEIYNWIDNFVAEHSNLVSKI 163

  Fly   203 ELGVSAQGRPILGVQIAFDNENRTTVFVESGIHAREWIAPATATYIIDQLVN--SKDSAVQALAR 265
            .:|.|.:.|.||.::.:....|||.:::::|||:||||..||..:|..::||  |||..::.:..
  Rat   164 HIGKSFENRSILVLKFSTGGPNRTAIWIDTGIHSREWITHATGIWISQKIVNAYSKDHVLKKVLN 228

  Fly   266 SQRWYIFPTVNPDGYQYTFKGDRMWRKNRALFG--ICRGVDLNRNFPFHWNVTGASGDPCRYDYS 328
            :...:|....||||:.:|...:|:||||:::..  :|.|||||||:...:...|::.:||...|.
  Rat   229 TMDIFIEIVTNPDGFAFTHSMNRLWRKNKSIQPGIVCVGVDLNRNWRTGFGGNGSNKNPCSETYR 293

  Fly   329 GPSAASEVETQRMIEFIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVDNYHDLTDIGKLAAN 393
            ||:..||.|...::.||   ......:..||:||||||:|:|||||.|.|.|:.:|.::.|.|..
  Rat   294 GPAPESEPEVAAIVAFI---TGHGNFKAMISIHSYSQMVMYPYGHSLEPVPNHKELFELAKDAVK 355

  Fly   394 KIKDVSGRIYKSGSIYETIYPSSGGSKDWAHGQLKIPITFSYELRGPADSEDLFILSAKEIEPTA 458
            .:..|.|..|..|||..|:|.:||.:.|||:.. .|...||:|||......  |:|.|.:|.|||
  Rat   356 ALYKVHGMEYIFGSISTTLYSASGITVDWAYDS-GIKYAFSFELRDTGQYG--FLLPASQIVPTA 417

  Fly   459 AEAFASIQTIVQEAGKRGY 477
            .|.:.:::||::......|
  Rat   418 EETWMALRTIMKHTLNHPY 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416	13/71 (18%)
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	110/297 (37%)
Cpa5	NP_001002808.2	Propep_M14	48..117	CDD:396700	13/68 (19%)
Cpa5	NP_001002808.2	M14_CPA	134..434	CDD:349442	111/305 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351675
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.750