DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4408 and cpb1

DIOPT Version :9

Sequence 1:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_001315354.1	Gene:	cpb1 / 322412	ZFINID:	ZDB-GENE-030131-1132	Length:	416	Species:	Danio rerio

Alignment Length:	450	Identity:	124/450 - (27%)
Similarity:	220/450 - (48%)	Gaps:	60/450 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 KTWLLLLLVSSVCVIQESKASSFCTKADQCALDEEIKTAADSVQARYDHTRIYQVELASEEHVRL 99
            |.:|||.||:                   .||.|.|....|         ::.|::..::|||.:
Zfish     2 KLFLLLGLVA-------------------VALCEPITFVGD---------KVLQLKPINDEHVTI 38

  Fly   100 FQAL----------EQASDSCSFMGHARQPGQKLTIMVTGAKVADFDDLVHSYNVTHRVLNYNFQ 154
            .:.|          .:::|..|.       ...:.|.|..|::|....::...::..:|:..|.|
Zfish    39 IRELGEKIKLDFWKPRSADLVSI-------DMTVDIHVPAAQLAMVSTILQQSDMEVKVMIDNLQ 96

  Fly   155 ALIDANYLEVAPEDTKPEEFDWKRYHPLESINAWLKKLAETHPEVLLVE-LGVSAQGRPILGVQI 218
            ..:.......:|  ||..  |:.:|:...:||.|...::..:|:::..: :|.:.:||.:..::|
Zfish    97 EAVKGQMDNRSP--TKGH--DYTKYNSWATINDWAISISSANPDLISRQSIGNTYEGRTMHLLKI 157

  Fly   219 AFD-NENRTTVFVESGIHAREWIAPATATYIIDQLVNS--KDSAVQALARSQRWYIFPTVNPDGY 280
            ..: ..|:..||::.|.||||||..|...:.:::.|::  .|..:..|.....:::.|..|.|||
Zfish   158 GKNTGSNKPAVFMDCGFHAREWITHAFCQWFVNEAVSTYGSDPDMTNLLDRMDFFVLPVFNIDGY 222

  Fly   281 QYTFKGDRMWRKNRA--LFGICRGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASEVETQRMIE 343
            :||:..||||||.|:  ....|.|.|.||||...|...|||.:||...|.|.|..||:|::.:..
Zfish   223 EYTWNRDRMWRKTRSKNSGSSCIGTDPNRNFNAGWCTVGASSNPCSDTYCGSSPESEIESKNLAN 287

  Fly   344 FIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVDNYHDLTDIGKLAANKIKDVSGRIYKSGSI 408
            ||  |.....|:.::::|||||:::|||.:..:...::.:|..:.:.|...::.:.|..|.||..
Zfish   288 FI--RTNKSVIKAYLTVHSYSQLLLFPYSYKYDLAAHHSELMSVSQGAIAALRSLYGTKYTSGPG 350

  Fly   409 YETIYPSSGGSKDWAHGQLKIPITFSYELRGPADSEDLFILSAKEIEPTAAEAFASIQTI 468
            ..||||::|||.|||: .|.:..::::|||.  :....|:|...:|:||..|...:::.|
Zfish   351 AATIYPAAGGSDDWAY-DLGVKYSYTFELRD--EGRYGFLLPESQIKPTCEETMLAVKYI 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416	14/80 (18%)
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	94/295 (32%)
cpb1	NP_001315354.1	M14_CPB	112..412	CDD:199852	95/302 (31%)
cpb1	NP_001315354.1	Propep_M14	27..99	CDD:280416	14/78 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593427
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.650