DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4408 and CG42264

DIOPT Version :9

Sequence 1:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_572260.2	Gene:	CG42264 / 31504	FlyBaseID:	FBgn0259149	Length:	634	Species:	Drosophila melanogaster

Alignment Length:	441	Identity:	121/441 - (27%)
Similarity:	205/441 - (46%)	Gaps:	61/441 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 VQARYDH----TRIYQVELASEEHVRLFQALEQASDSCSFMGH-------ARQPGQKLTIMVTGA 130
            :..||.:    .|.|..:|......||.|...:|     |..|       ..|.|  :.|::...
  Fly   207 INRRYRNGSQVQRYYGFQLWKVHETRLEQPELRA-----FWRHFGSEVWNINQDG--IDILIEQR 264

  Fly   131 KVAD----FDDLVHSYNVTHRVLNYNFQALIDANYLEVA----PEDT-----------KPEEFDW 176
            .|||    .|.:.:|||    ::..:.::.||.:|:||.    |.|:           .....:|
  Fly   265 NVADARKFMDKVGYSYN----IMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPWMEVPGSTMNW 325

  Fly   177 KRYHPLESINAWLKKLAETHPE-VLLVELGVSAQGRPILGVQIAFDNENRTTVFVESGIHAREWI 240
            :|||....|..:|:.|.||:.| |.|:::||:...||:..::::..|.:...|||::|:.||:|:
  Fly   326 RRYHDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEVIRVSNGNPDNWAVFVDAGLQARDWL 390

  Fly   241 APATATYIIDQLVN-------------SKDSAVQALARSQRWYIFPTVNPDGYQYTFKGDRMWRK 292
            :||..||.|.:|.:             .:.|..:...|...||..|..|||||||:.:.||:|.|
  Fly   391 SPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGYQYSRQTDRLWTK 455

  Fly   293 NRALFGI--CRGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASEVETQRMIEFIRHRVESERIR 355
            ||....:  |.||:|:|||.:.|:.||::.:||:..|.|..:.||.|::.:..|:...  .|.:.
  Fly   456 NRGYDSVSGCYGVNLDRNFDYGWDGTGSTSNPCKNLYRGAHSFSEPESRAVCSFLSGM--REYLG 518

  Fly   356 TFISLHSYSQMIMFPYGHSAERVDNYHDLTDIGKLAANKIKDVSGRIYKSGSIYETIYPSSGGSK 420
            .::||..|.|.|.:|:|.:....:|..:|....:.|...::.::...|.||:.|.......|.|.
  Fly   519 AYVSLGGYGQAITYPWGDADYVTENQRNLKQTARRAVLALRRLNQAEYSSGTSYRQKLARPGNSA 583

  Fly   421 DWAHGQLKIPITFSYELRGPADSEDLFILSAKEIEPTAAEAFASIQTIVQE 471
            ||...::...:.|:..|:.  .....::|....|..:..|.|..::.|.|:
  Fly   584 DWVQDRIGPQLVFNMFLKD--QGRYGYLLPPHYIVESGEEVFEFLRIIAQQ 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416	18/81 (22%)
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	91/309 (29%)
CG42264	NP_572260.2	Propep_M14	<241..293	CDD:280416	13/57 (23%)
CG42264	NP_572260.2	M14_CP_A-B_like	328..633	CDD:199844	91/309 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I1180
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	8	7.900